LifeArc

How would you describe LifeArc in one word? We asked our team... Many of the words they chose reflect the heart of what we stand for at LifeArc: 🌟 Focus on patient impact – We are always open and transparent and strive to do the best we can to transform lives. 🌟 Innovation – We encourage curiosity and creative thinking so that we can turn ideas into impactful solutions. 🌟 Collaboration – We value different perspectives and experiences, trust each other, enjoy our work and share our successes. 🌟 Commitment – We are committed to finding solutions to complex problems by embracing ambiguity and adopting a flexible approach. 🌟 Excellence – We thrive in a high-performance culture and are driven by both personal and organisational objectives. We bring these values to every project and partnership and always put patients at the centre of everything we do. Find out more about what it's like to work with us and explore our vacancies: https://lnkd.in/eFyh-PQ9

We’re in the running for the Smiley Charity Film Awards! These awards celebrate cause-based films that raise awareness of important issues and inspire action for change. In partnership with Asthma + Lung UK, we created a film to highlight the challenges people with chronic lung conditions face, from delayed diagnoses to learning how to manage their health. Conditions like bronchiectasis are often underdiagnosed and poorly understood, leaving many without the care they need for far too long. In this clip, Charlotte shares the story of her son Felix, who was diagnosed with bronchiectasis. Due to a lack of effective treatments, his daily life now includes airway clearances, and he is at risk of flare-ups and deteriorating lung health. We hope to raise awareness of this overlooked condition and highlight the urgent need for new innovations to improve lung health and the lives of people living with bronchiectasis.  If you support our cause, please vote for us! 👉 https://lnkd.in/ea4mbQfc 

Our New Year's resolution is to share more photos from our in-house imaging hub. We'll be sharing one per month throughout 2025. For January, we're sharing some white and snowy iPSC-derived motor neurons from our iPSC platform with B3-tubulin expression, a neurite marker used as part of our in-house quality control. Photo credit: Will Stebbeds

Reflecting on 2024: A snapshot of our year! 🚀 As 2024 draws to a close, we're proud to reflect on an incredible year of delivering great science, strengthening connections across the ecosystem, and accelerating progress to bridge the gap between the lab and the clinic. 🌐 Through our Translational Challenges, we continued to engage with experts and patient communities to accelerate solutions for underserved health conditions. • This year, we established disease-focussed networks in the UK that enable new, joined up ways of working, such as our Translational Centres for Rare Disease and the Translational Innovation Hub Network for Lung Health and Infection in Cystic Fibrosis. • In partnership with industry leaders Cancer Research Horizons, Innovate UK and Medicines Discovery Catapult, we launched the groundbreaking initiatives C-Further and PACE-AMR to tackle the biggest challenges in childhood cancer and AMR, respectively. • We have expanded our global impact through meaningful collaborations like ASPIRE, in collaboration with ReAct - Action on Antibiotic Resistance, and the launch of the new Centre for Translational AMR Research (CTAR) at the Drug Discovery and Development Centre (H3D), University of Cape Town. 🔬Our brilliant team of scientists have relentlessly supported our partners through our many capabilities, including data science, assay development, and antibody humanisation and discovery, including launching our cutting-edge antibody discovery platform, B-SMArT. 📚 Along the way, we've shared our learnings with the community and published dozens of resources created in collaboration with experts and patients. These include: the MND Insights Report and MND Biomarker Roadmap Report, made possible by our MND Insights group; the Guide to Impact and Theory of Change; the Transforming Respiratory Health Report (created in partnership with Asthma + Lung UK); and the Childhood Cancer Unmet Needs Report. We're incredibly proud of what we've accomplished in 2024 and are excited to keep building on this momentum in 2025 by continuing to use our translational expertise to create lasting impact for patients.

✨ It’s been a great year here at CF AMR Syndicate, 2024 has been full of exciting developments and milestones. As we close out the year, we reflect on some of our highlights.   We look forward to achieving great things in 2025, working alongside our colleagues and partners.   #CFAMR #CysticFibrosis #DrugDiscovery #Therapeutics #Diagnostics

We are delighted to announce the appointment of Jonathan Morgan as LifeArc's first Chief Medical Officer. Jonathan will join us in January 2025 from Renaissance Pharma, where he led the clinical and regulatory functions of a newly established biotech, focusing on the development of a monoclonal antibody in paediatric oncology. He has almost 25 years of experience in the healthcare industry, with leadership positions across large global pharmaceuticals and biotech. His wealth of knowledge extends across all key medical functions, including clinical development, medical affairs and safety. As Chief Medical Officer, Jonathan will play a crucial role in shaping our clinical research agenda and supporting clinical development programmes, with a focus on advancing promising innovations for underserved health conditions. We look forward to welcoming him in the new year!

"This is a really exciting time to be involved in bronchiectasis research." says Professor Amelia Shoemark, an expert in respiratory research at the University of Dundee. 📈 With the incidence of bronchiectasis on the rise, it's more important than ever to challenge misconceptions and raise awareness about this often-overlooked condition. 🔬 Thanks to large-scale studies, significant strides have been made in understanding key factors involved in bronchiectasis, such as infection, inflammation, and the body's ability to clear mucus from the lungs. Now, we must build on this foundation, deepen our understanding, and advance research into clinical trials to improve quality of life for patients. Do you have expertise in chronic respiratory conditions? We want to work with you! We're collaborating Asthma + Lung UK and industry leaders to accelerate innovation and research in bronchiectasis. ➡️ Find out how we can support your work and join us in driving meaningful change: https://lnkd.in/eMDiNj84

We are delighted to announce that Fiona Roberts has been appointed as LifeArc's Chief People Officer with effect from December 2024. Fiona has a wealth of experience in people leadership, having held HR roles across various sectors throughout her career, including at Volkswagen, The Open University, Carillion Plc and BAA. Fiona held the position of Chief People Officer at The Crick from 2019 until 2023. At The Crick, Fiona helped to reshape learning and development, as well as approaches to health, wellbeing and a listening culture, whilst leading the people agenda, academic training for early career researchers and the science support and service delivery teams. Since then, Fiona has served as Chief People Officer at Kings College London, where she has had significant impact, truly placing People at the centre of the organisation's strategy and vision. We look forward to welcoming Fiona as we continue to drive more innovative therapies toward the patients who need them most.

We often get asked, "How do we decide what areas of health to focus on?" As a self-funded charity, we can focus on finding solutions to medical challenges where our translational science expertise can have the greatest impact. These often have a high unmet patient need and promising science that is ripe for translation, among other factors. As such, we have chosen to focus on the following Translational Challenges: 🔬 Global Health (focussing on antimicrobial resistance and neglected tropical diseases) 🔬 Motor Neuron Disease 🔬 Chronic Respiratory Infection 🔬 Rare Disease 🔬 Childhood Cancer With our expertise and support, we strive to accelerate the progression of promising discoveries in these areas out of the lab and towards patients. Find out more about our Translational Challenges: https://lnkd.in/ePFc9mzK

We’re so excited that our film, “Every breath - living with a chronic lung condition and the need for more support”, is an entrant in this year’s Smiley Charity Film Awards! We teamed up with Asthma + Lung UK to create this film which shows the daily challenges faced by people living with chronic lung conditions like bronchiectasis, COPD, and asthma, and how hard it can be to get a diagnosis and the right care.  In this clip, Felicity talks about her journey with COPD. She shares how delays in diagnosis meant she suffered repeated serious infections before finally getting the care she needed. With faster diagnosis and better treatments, we can help people like Felicity recover more quickly and have a better quality of life. As the world’s largest cause-based film campaign, these awards provide a powerful platform to amplify awareness and share vital messages about important subjects. Through our video, we aim to shine a light on why research into chronic lung infections is so important – something we’re passionate about supporting here at LifeArc.  Please vote for us and help spread the word—we’d love your support to get to the next stage!👉 https://lnkd.in/ea4mbQfc