NunaBio Limited

𝗪𝗲 𝗮𝗿𝗲 𝗲𝘅𝗰𝗶𝘁𝗲𝗱 𝘁𝗼 𝘀𝗵𝗮𝗿𝗲 𝗼𝗻𝗲 𝗺𝗼𝗿𝗲 𝗰𝗼𝗺𝗽𝗮𝗻𝘆 𝗺𝗶𝗹𝗲𝘀𝘁𝗼𝗻𝗲 𝗶𝗻 𝘁𝗶𝗺𝗲 𝗳𝗼𝗿 𝗖𝗵𝗿𝗶𝘀𝘁𝗺𝗮𝘀! 🎄 🎉   Earlier this year, we produced fully synthetic pDNA which was successfully cloned into cells. Now, we’ve taken this a step further and 𝗽𝗿𝗼𝗱𝘂𝗰𝗲𝗱 𝗳𝘂𝗹𝗹𝘆 𝘀𝘆𝗻𝘁𝗵𝗲𝘁𝗶𝗰 𝗺𝗶𝗻𝗶𝗰𝗶𝗿𝗰𝗹𝗲 𝗗𝗡𝗔 (𝗺𝗰𝗗𝗡𝗔). mcDNA has a higher efficiency, better stability and improved safety compared to pDNA.   Using our enzymatic technology, we have produced a 𝗽𝗿𝗼𝗼𝗳 𝗼𝗳 𝗰𝗼𝗻𝗰𝗲𝗽𝘁 𝟭.𝟯𝗸𝗯 𝗺𝗰𝗗𝗡𝗔 𝘀𝗲𝗾𝘂𝗲𝗻𝗰𝗲 𝘄𝗵𝗶𝗰𝗵 𝗶𝗻𝗰𝗹𝘂𝗱𝗲𝗱 𝗮 𝟭𝟱𝟬𝗯𝗽 𝗽𝗼𝗹𝘆-𝗔 𝗿𝗲𝗴𝗶𝗼𝗻 𝘄𝗶𝘁𝗵 𝗹𝗲𝘀𝘀 𝘁𝗵𝗮𝗻 𝟭% 𝗺𝗶𝘅𝗲𝗱 𝗽𝗼𝗽𝘂𝗹𝗮𝘁𝗶𝗼𝗻. Made in an entirely synthetic and cell-free manner, this showcases the potential for significant cost and time savings using NunaBio Limited’s technology.     We are looking forward to testing our mcDNA in NB3 to produce mg-scale in a matter of hours.     Currently, we’re finalising our production process, but we’re confident that in early 2025, we’ll be able to launch mcDNA as a product, for various fields including Cell and Gene Therapies, Biologics, and more.    If you’re interested in learning more about mcDNA, or want to be the first to hear about our product launches, visit www.nunabio.com or get in touch.    As 2024 draws to a close, we want to thank the talented team behind NunaBio, none of the progress this year would have been possible without their hard work and innovation.    𝗪𝗶𝘁𝗵 𝟮𝟬𝟮𝟱 𝗳𝗮𝘀𝘁 𝗮𝗽𝗽𝗿𝗼𝗮𝗰𝗵𝗶𝗻𝗴, 𝘁𝗵𝗲𝗿𝗲’𝘀 𝗽𝗹𝗲𝗻𝘁𝘆 𝗼𝗻 𝘁𝗵𝗲 𝗵𝗼𝗿𝗶𝘇𝗼𝗻 𝗳𝗼𝗿 𝘂𝘀, 𝘀𝗼 𝘀𝘁𝗮𝘆 𝘁𝘂𝗻𝗲𝗱 𝘁𝗼 𝗳𝗶𝗻𝗱 𝗼𝘂𝘁 𝗺𝗼𝗿𝗲…    #mcDNA #CellFree #Enzymatic #SyntheticDNA #NunaBio 

𝗪𝗲 𝗮𝗿𝗲 𝗲𝘅𝗰𝗶𝘁𝗲𝗱 𝘁𝗼 𝘀𝗵𝗮𝗿𝗲 𝗼𝗻𝗲 𝗺𝗼𝗿𝗲 𝗰𝗼𝗺𝗽𝗮𝗻𝘆 𝗺𝗶𝗹𝗲𝘀𝘁𝗼𝗻𝗲 𝗶𝗻 𝘁𝗶𝗺𝗲 𝗳𝗼𝗿 𝗖𝗵𝗿𝗶𝘀𝘁𝗺𝗮𝘀! 🎄 🎉   Earlier this year, we produced fully synthetic pDNA which was successfully cloned into cells. Now, we’ve taken this a step further and 𝗽𝗿𝗼𝗱𝘂𝗰𝗲𝗱 𝗳𝘂𝗹𝗹𝘆 𝘀𝘆𝗻𝘁𝗵𝗲𝘁𝗶𝗰 𝗺𝗶𝗻𝗶𝗰𝗶𝗿𝗰𝗹𝗲 𝗗𝗡𝗔 (𝗺𝗰𝗗𝗡𝗔). mcDNA has a higher efficiency, better stability and improved safety compared to pDNA.   Using our enzymatic technology, we have produced a 𝗽𝗿𝗼𝗼𝗳 𝗼𝗳 𝗰𝗼𝗻𝗰𝗲𝗽𝘁 𝟭.𝟯𝗸𝗯 𝗺𝗰𝗗𝗡𝗔 𝘀𝗲𝗾𝘂𝗲𝗻𝗰𝗲 𝘄𝗵𝗶𝗰𝗵 𝗶𝗻𝗰𝗹𝘂𝗱𝗲𝗱 𝗮 𝟭𝟱𝟬𝗯𝗽 𝗽𝗼𝗹𝘆-𝗔 𝗿𝗲𝗴𝗶𝗼𝗻 𝘄𝗶𝘁𝗵 𝗹𝗲𝘀𝘀 𝘁𝗵𝗮𝗻 𝟭% 𝗺𝗶𝘅𝗲𝗱 𝗽𝗼𝗽𝘂𝗹𝗮𝘁𝗶𝗼𝗻. Made in an entirely synthetic and cell-free manner, this showcases the potential for significant cost and time savings using NunaBio Limited’s technology.     We are looking forward to testing our mcDNA in NB3 to produce mg-scale in a matter of hours.     Currently, we’re finalising our production process, but we’re confident that in early 2025, we’ll be able to launch mcDNA as a product, for various fields including Cell and Gene Therapies, Biologics, and more.    If you’re interested in learning more about mcDNA, or want to be the first to hear about our product launches, visit www.nunabio.com or get in touch.    As 2024 draws to a close, we want to thank the talented team behind NunaBio, none of the progress this year would have been possible without their hard work and innovation.    𝗪𝗶𝘁𝗵 𝟮𝟬𝟮𝟱 𝗳𝗮𝘀𝘁 𝗮𝗽𝗽𝗿𝗼𝗮𝗰𝗵𝗶𝗻𝗴, 𝘁𝗵𝗲𝗿𝗲’𝘀 𝗽𝗹𝗲𝗻𝘁𝘆 𝗼𝗻 𝘁𝗵𝗲 𝗵𝗼𝗿𝗶𝘇𝗼𝗻 𝗳𝗼𝗿 𝘂𝘀, 𝘀𝗼 𝘀𝘁𝗮𝘆 𝘁𝘂𝗻𝗲𝗱 𝘁𝗼 𝗳𝗶𝗻𝗱 𝗼𝘂𝘁 𝗺𝗼𝗿𝗲…    #mcDNA #CellFree #Enzymatic #SyntheticDNA #NunaBio 

Yesterday was Christmas Jumper day at NunaBio Limited to raise money for Save the Children UK. We think that the team did a great job - particularly Steven Evans and Osama El-Zubir, who shared one jumper! Also, we wanted to give a special shout out to the Logistics company who photobombed our impromptu shoot. #Christmasjumperday #savethechildren #photobomb

It was the Christmas party for NunaBio Limited at the Earl of Pitt Street last night. A good time was had by all - and the team has grown so much since last year. We're all really looking forward to 2025! #christmasparty #growingteam #

Following on from our recent post about our new NB3 system, we are delighted to share yet another milestone which takes us a step closer to the launch of a new product.   Out talented team have successfully produced batches of up to 1mg of pure poly-A tails with lengths ranging from 50bp to 150bp.   Although this was a proof of concept, we're now looking forward to testing this sequence in NB3, capable of producing 40mg of DNA in just 80 minutes, to continue pushing the limits of what we can do.   And that's not all! We are also working on doubling our maximum poly-A length, aiming to reach 300bp or higher in 2025 using our groundbreaking and patented 'NanoRobots' technology.   Early next year we plan to launch our long, pure poly-A tails as a product. They will be offered at up to mg-scale with 150bp custom adapters available at either the 5’ end, the 3’ end or both.   We will produce sequences that nobody else offers, at scales not seen before for poly-A. This will be a game-changing offering for those involved in a variety of fields including mRNA, circular DNA and more.   If you’re interested in learning more about our poly-A offering or want to join our waiting list for material, get in touch or visit www.nunabio.com.   None of this would be possible without the hardworking team at NunaBio Limited. There’s still more to come before the end of the year, so watch this space!     #PolyA #Innovation #SyntheticDNA #Enzymatic  

Happy Thanksgiving from the team at NunaBio Limited! Time to rest and relax (and eat too much)! #happythanksgiving #toomuchturkey #nearlyChristmas

🎉 A new milestone for NunaBio Limited - at least on Linkedin!🎉 Thanks to Steve Green - follower number 1500! Always great to start the week on a high! #newfollower #number1500

Great update from Joe Hedley, our CEO. Really exciting times here at NunaBio Limited! If you want to know more about our "black box" NB-3 or our capabilities, please drop us a line.

Endotoxin clearance is critical for patient safety for drugs made using gram-negative bacteria, like E.coli. However, the gold standard limulus amebocyte lysate (LAL) test is made using the blood of the horseshoe crab. Over 700,000 horseshoe crabs are harvested per year for this purpose, and it is estimated that up to 30% die in the process. Populations of this crab are declining for several reasons, so a new approach is required. New technologies for DNA synthesis and amplification have the potential to completely remove the need for E.coli and the risk of endotoxin contamination. NunaBio Limited is proud that its technology is sustainable - we just didn't realise it was good for crab populations too! #horseshoecrabs #endotoxinfree

Over the past couple of weeks, NunaBio Limited has had some IT issues. You may have noticed that our website has not been available. Unfortunately, although we do make complex DNA, it turns out we can't solve complex IT problems! So we have to thank Aspire Technology Solutions and THUMB DESIGN for all their help in getting everything back up and running as of today. If you've recently sent us an email and have not had a reply, this is probably why. Please get in touch if you need any further information.