Things we love to see! And just in time for Christmas, too. A wonderful collaborative effort between two of our NUSMED Immunology TRP researchers, Haiyan Liu and Herbert Schwarz and their respective teams with an original research article in Oncoimmunology on Tregs and CD137! Read more about it at: https://lnkd.in/gpFd6cSz
About us
The NUSMed Immunology Translational Research Programme aims to understand the role of the immune system in health and diseases. The programme strives to enable the discovery and development of more effective immunotherapy, new treatment guidelines and diagnostic tests for patients with disease-specific problems such as autoimmune and airway diseases, cancer, chronic inflammation, infections and organ/ tissue transplantation. These goals will be achieved by fostering collaborative research and advancing latest technologies to probe immunological mechanisms, and by enhancing infrastructure for clinical translation. Three themes have been identified in this programme which will be supported by shared technologies and cores: 1. Immune homeostasis – to advance understanding the role of the immune system in health and diseases and its regulation. 2. Immunotherapies – to advance and deliver innovative immune-based therapies to patients. 3. The Asian immunophenotype and clinical investigations – to develop and circulate novel approaches to diagnose, guide treatment and measure therapy efficacy.
- Industry
- Research Services
- Company size
- 51-200 employees
- Headquarters
- Singapore
- Type
- Educational
- Specialties
- Immunophenotyping, Autoimmunity, Immunotherapies, and Immune homeostasis
Locations
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Primary
Get directions
28 Medical Drive
Singapore, 117456, SG
Updates
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Well done Hong Yong Peh!
Excited to share my first corresponding author review article entitled "Pro-resolving lipid mediators and therapeutic innovations in resolution of inflammation", published in Pharmacology & Therapeutics. Read at: https://lnkd.in/eBWPHmeN This was a joint effort with Jianmin Chen where we provided updates in the field of resolution of inflammation using either pro-resolving lipid mediators (lipoxins, resolvins, protectins, maresins) or annexin mimetics. The HYPRI lab is setting up the LC-MS/MS targeted lipidomics platform as well to profile in biological samples, besides assessing how these bioactive lipid mediators can accelerate the resolution of inflammation. #HYPRI #PharmacoNUS NUSMED Immunology TRP, SLING - Singapore Lipidomics Incubator, Department of Pharmacology, NUS Medicine, National University of Singapore
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Professor Nicholas Gascoigne and his lab has just published an outreach article in the leading science communication publication, Scientia! Harnessing his decades of CAR T-cell research, he has discovered that CD28-CAR T-cell activation through FYN kinase signalling rather than LCK enhances their therapeutic performance in combating cancer, with the potential of revolutionising cancer immunotherapy as a mode of treatment. Congrats, Nick and team!
Dr Nicholas Gascoigne is harnessing the immune system’s power to fight cancer, offering new hope in innovative immunotherapy treatments. https://lnkd.in/ejAexV3Y Discover how this research could transform cancer care: https://lnkd.in/e-7tykDJ
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A/Prof Joshua Ooi will be giving a seminar on 16 September, where he will share on his development of genetically-engineered antigen-specific Treg to suppress pathogenic autoreactivity in lupus. The NUSMED ITRP Seminar Series aims to highlight the latest research in immunology and immunity in Asia and around the world. #lupus #Tregs #autoimmunity
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Work in Progress is back for the month of August! Join us at our cosy lounge as Hoa (Nguyen Lab) and Jun Hao (Liu Lab) present bite-size updates on their current research project! Light refreshments will be provided. Many thanks to our kind sponsor Global Cold Chain Solutions Pte Ltd!
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RESCHEDULED TO 28 AUGUST 2024: NUSMED Immunology TRP will be hosting Dr Girija Goyal, an immunologist and organ-on-chip expert on Wednesday, 28 August 2024 at 12m, where she will present an overview on organs on chip research, as well as selected examples from research programs that she's currently leading. The NUSMED ITRP Seminar Series aims to highlight the latest research in immunology and immunity in Asia and around the world.
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NUSMED Immunology TRP will be hosting Dr Olivia Majer as she shares her research on nucleic acid detection in immune homeostasis, and how mutations in these immune pathways are linked to the development of childhood-onset lupus. The NUSMED ITRP Seminar Series aims to highlight the latest research in immunology and immunity in Asia and around the world. #lupus #autoimmunity #pathwaymutations #tolllikereceptors
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The NUSMED Immunology TRP Research in Progress returns with a new name! Join us tomorrow afternoon at NUSMed ITRP Work in Progress for a pair of short presentations from two of our best junior researchers--Cheok Yi Ying and Emily Nickles!
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We're always extra happy when our alumni come back for a visit and let us know what they've been up to recently! A graduate of Prof Herbert Schwarz's lab, Dr Qun Zeng will be giving a seminar on his recent work (published in Cell) on the functional significance of circadian dynamics in the tumor microenvironment, and how these can be harnessed to improve the efficacy of immunotherapy treatments to achieve better patient outcomes. #carTcells #tumourmicroenvironment #cancerimmunotherapy #circadianrhythm #IPalumni
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Well done Long Nguyen and lab!
Led by Assoc Prof Nguyen Nam Long, researchers from the NUSMED Immunology TRP at #NUSMedicine unexpectedly discovered that an orphan transporter called protein Mfsd7c transports excessive choline out of the blood-#brain barrier, instead of ingesting choline like other organs do. Choline is a micro-nutrient especially needed by the brain and nervous system to regulate memory, moods and muscle control. This finding opens new avenues for understanding #neurological diseases and improving related therapeutics. #NewsandUpdates Read more: https://lnkd.in/ggzq6_39
Little-known protein choline transporter in brain may be key therapeutic target for ageing and Alzheimer’s disease - NUS Yong Loo Lin School of Medicine
https://medicine.nus.edu.sg