CHEManager International

Immedica Pharma AB to Acquire Biopharma Company Marinus Pharma Sweden-headquartered global rare disease company Immedica Pharma has agreed to acquire Marinus Pharmaceuticals, a US commercial-stage pharmaceutical company developing therapies for seizure disorders, for enterprise value of approximately $151 million. With the deal, Immedica will add ZTALMY (ganaxalone) oral suspension, CV, to its portfolio. A neuroactive steroid gamma-aminobutyric acid (GABA)-A receptor positive modulator, ZTALMY has been approved by the US Food and Drug Administration (FDA) in March 2022 for the treatment of seizures associated with cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) in patients two years of age and older. The #acquisition is expected to accelerate Immedica’s growth into the North American market, providing an immediate revenue-generating rare disease product and an experienced commercial team. Find out more on #CMI online: https://lnkd.in/eh9ne_C3

2025 Media Guide CHEManager & CHEManager International #CHEManager, the leading trade and business newspaper for the management in the chemical and pharmaceutical industry. ▶️ CHEManager supplies managers and executives periodically with important news to assist them in making strategic business and investment decisions. Latest news, insightful inter views, substantiated market reports and technical articles provide CHEManager readers in Germany, Switzerland and Austria with a headstart on crucial information 12 times per year. ▶️ Two times a year, CHEManager interviews top executives to compile the substantiated business survey CHEMonitor. CHEManager’s penetration of the management levels of chemical and pharmaceutical companies – for instance all members of the VAA (German Association of Chemical Executives) – with a circulation of 30,000 copies plus 14.000 e-Paper is unique. ▶️ The CHEManager brand family is complemented by the B2B online portal www.chemanager.com with a biweekly news letter as well as internationally distributed English-language special-topic tabloids under the CHEManager International brand (4 issues per year, circulation 30,000 copies) and the corresponding English-language online portal. ▶️ Thus, the CHEManager brand is the ideal year-round, cross-media image vehicle for corporate advertising campaigns, product promotion, recruitment advertisements and online marketing. Find out more in our 2025 Media Guide: https://lnkd.in/eaeCHvCX

Innovent Licenses Lung #Cancer Therapy Candidate to Roche Chinese biopharmaceutical company Innovent Biologics announced a collaboration and exclusive license agreement with Roche to advance the development of IBI3009, a novel DLL3-targeted antibody-drug conjugate (ADC) candidate. Under the agreement, Innovent has granted Roche exclusive global rights to develop, manufacture and commercialize IBI3009. The two parties said that they will jointly focus on the early-stage development of this ADC candidate, after which Roche will take over full development. Innovent will receive an upfront payment of $80 million and is eligible to receive up to $1 billion in development and commercial milestone payments, along with tiered royalties on net sales. IBI3009 targets DLL3, an #antigen with low expression in normal tissues but significantly overexpressed in certain cancers, particularly small-cell lung cancer and other #neuroendocrine tumors. Read more on #CMI online: https://lnkd.in/ek-3tVXa

NEXTCHEM Wins Two Contracts in Canada NextChem, part of Italian engineering group Maire Tecnimont, has been awarded new contracts for the proprietary NX STAMI #Urea technology of its subsidiary Stamicarbon in Canada. The first award covers the process design package (PDP) and licensing for an integrated urea and diesel exhaust fluid (DEF) plant being developed by farmer-owned consortium Genesis Fertilizers in Belle Plaine, Saskatchewan, Canada. The plant will have a urea melt capacity of 2,500 metric tons per day (MTPD), with operations expected to begin by 2029. With a planned carbon capture and sequestration unit, it will be the first proposed low-carbon nitrogen #fertilizer plant in Canada, NextChem said. The facility will also include a DEF facility with a production capacity of 1,500 MTPD. DEF, also known as #AdBlue in Europe, is a 32.5% high-purity urea solution in deionized water, developed to reduce NOx emissions from diesel engines. Read more on #CMI online: https://lnkd.in/ehur9cZh

HUTCHMED to Divest Stake in Joint Venture for $608 Million China’s Hutchmed has agreed to divest its 45% equity interest in Shanghai Hutchison Pharmaceuticals Ltd. (SHPL) for approximately $608 million (4,478 million renminbi) in cash, to #China-based private equity firm GP Health Service Capital and Shanghai Pharmaceuticals Holding Co., Ltd.. SHPL, a 50:50 joint venture established between Hutchmed and Shanghai Pharmaceuticals in 2001, primarily manufactures its own-brand prescription medicines in China, predominantly for cardiovascular diseases. According to Hutchmed, its consolidated net income in 2023 from SHPL was $47.4 million. Hutchmed said that these transactions would allow it to focus on its core business of discovering, developing and commercializing novel therapies for the treatment of cancers and immunological diseases, including advancing its next-generation antibody-drug conjugate (ADC) platform. By combining #antibodies with targeted therapeutics instead of cytotoxins, these antibody-targeted therapy conjugates (ATTCs) offer dual mechanisms for addressing a target. Hutchmed plans to move the first of these ATTCs into clinical trials in the second half of 2025. Read more on #CMI online: https://lnkd.in/eFdtnb2H

Carbios Postpones Construction of PET Bio-Recycling Facility in #France French green chemistry company CARBIOS announced that it is postponing the construction of its #PET bio-recycling plant in Longlaville for six to nine months due to delayed funding pending completion of additional financing under satisfactory conditions. The company aims to complete the #financing as soon as possible to meet market needs from 2027. Carbios expects to sign several binding commercial contracts in the first half of 2025. According to Carbios, the decision to defer the construction of the plant does not call into question the project, but it does allow the company to slow down the rate of cash consumption and to continue commercial discussions in a cash-neutral manner. With the planned delay in the construction of the Longlaville plant and tighter control of expenditure, Carbios said that it is “well positioned to meet its needs beyond the next twelve months.” Find out more on #CMI online: https://lnkd.in/eNFVDzge

CHEManager is a media partner of the Pharmaceutical Manufacturing and Packaging Congress (PHARMAP) 2025. The PHARMAP Congress 2025, organized by BGS Medical Events, takes place on April 14-15 in Berlin, Germany, and welcomes decision-makers from Bayer, Merck, Takeda, Ferrer, Roche, Produlab Pharma, Johnson & Johnson, and others. Delegates have an opportunity to explore topics such as sustainable packaging solutions; AI and robotics in pharma manufacturing; blockchain, IoT, AI in pharma supply chain; approaches for peak performance in pharma manufacturing; selection and management of outsourcing partners; and operational challenges in manufacturing digitalization. Become a part of the networking at PHARMAP 2025: https://sh.bgs.group/26j #PHARMAP2025 #packaging #manufacturing #pharma

#CMI0424: Transforming Distribution Strategies (Statement 14/14) CHEManager asked executives and industry experts from a broad range of chemical distributors to share their views on how their companies are dealing with this changing economic environment and the resulting opportunities and challenges. We proposed to discuss the following aspects: ▶️ Which developments, both among your customers and the distributors themselves, do you see as challenges for the sector—and which as opportunities? ▶️Amid economic and geopolitical challenges, chemical distributors face investment uncertainties. In which areas do you think investment is nevertheless essential? ▶️Innovation is a key growth driver in the specialty chemicals market. How can distributors effectively support innovation on both the supplier and the customer side? Read the insightful statement from Arthur Jaunich, CEO, STOCKMEIER Gruppe Chemicals: ▶️Optimism and Growth Amid Economic Challenges The current European economic environment remains challenging, with structural issues—for example, high energy costs, excessive regulation, or scarcity of labor—limiting the competitiveness and growth prospects of many industrial producers. Also, chemical #distribution, especially in basic chemicals, is impacted by slowing demand and price erosion. We expect market consolidation to further accelerate in the chemical distribution sector. Still, we at Stockmeier Chemicals, stay optimistic. As a chemical distributor, we support our customers with an efficient, reliable, and safe supply of a broad portfolio of chemicals. We help optimize product sourcing and logistics, provide support related to regulation and #sustainability, and offer individual toll manufacturing solutions. At Stockmeier Chemicals we keep investing in our offering of value-added services to best support our customers in building their competitive edge. (...) Find out the full statement on #CMI online: https://lnkd.in/ebWYdsDG

#CMI0424: Transforming Distribution Strategies (Statement 13) CHEManager asked executives and industry experts from a broad range of chemical distributors to share their views on how their companies are dealing with this changing economic environment and the resulting opportunities and challenges. We proposed to discuss the following aspects: ▶️ Which developments, both among your customers and the distributors themselves, do you see as challenges for the sector—and which as opportunities? ▶️Amid economic and geopolitical challenges, chemical distributors face investment uncertainties. In which areas do you think investment is nevertheless essential? ▶️Innovation is a key growth driver in the specialty chemicals market. How can distributors effectively support innovation on both the supplier and the customer side? Read the insightful statement from Dany NJEIM, CEO, RN CHEMICALS: ▶️Seizing Growth through Digital #Transformation In the current landscape, distributors in the chemical sector face several significant challenges. Supply chain disruptions require them to adapt swiftly to unforeseen events and find effective ways to mitigate their impact. Additionally, the increasing regulatory complexity demands that distributors stay updated on evolving regulations to ensure compliance, thereby avoiding potential legal and financial penalties. They also grapple with #sustainability and environmental concerns, needing to balance profitability with their responsibility towards the environment. Furthermore, #cybersecurity threats pose a risk, necessitating investments in robust measures to protect sensitive data and prevent cyberattacks. Despite these challenges, there are also notable opportunities for growth. Digital transformation presents significant prospects for the chemical distribution sector, enabling distributors to leverage technology for enhanced efficiency. By offering value-added services such as formulation development, technical support, and customized solutions, distributors can differentiate themselves in a competitive market. Embracing sustainability and the circular economy not only leads to cost savings but also improves brand reputation and fosters increased customer loyalty. Lastly, global expansion into new markets can open up fresh avenues for growth, allowing distributors to tap into emerging opportunities. (...) Read the full statement on #CMI online: https://lnkd.in/eni728EZ

#CMI0424: Transforming Distribution Strategies (Statement 12) CHEManager asked executives and industry experts from a broad range of chemical distributors to share their views on how their companies are dealing with this changing economic environment and the resulting opportunities and challenges. We proposed to discuss the following aspects: ▶️ Which developments, both among your customers and the distributors themselves, do you see as challenges for the sector—and which as opportunities? ▶️Amid economic and geopolitical challenges, chemical distributors face investment uncertainties. In which areas do you think investment is nevertheless essential? ▶️Innovation is a key growth driver in the specialty chemicals market. How can distributors effectively support innovation on both the supplier and the customer side? Read the insightful statement from Dr. Gerd Bergmann, Managing Director, Nordmann: ▶️Eco-Friendly Demand Drives Opportunity The chemical industry currently faces numerous, partly unprecedented challenges, including high energy and fluctuating raw material prices, regulatory burdens and geopolitical tensions. These factors impact customers in the manufacturing industry and thus also distributors, resulting in a weaker demand. New technologies, which are rapidly evolving, offer many opportunities for increasing efficiency and developing products. Mastering (master) data and external market knowledge is a decisive factor for future success. We are heavily investing in the #digitalization of processes to make faster, success-oriented, data-based decisions. The demand for eco-friendly and sustainable products offers opportunities for visionary companies investing in green technologies, recycling processes and sustainable practices but is often still too price driven. (...) Read the full statement on #CMI online: https://lnkd.in/eNCiviNV