Zymvol Biomodeling

#HIRING We’re looking for new members to join #TeamZymvol. Head to Zymvol Careers (https://lnkd.in/ez-hzFn) to see all our current job openings: → Business Development Manager & Team Lead (PhD or MSc in Life Sciences.) → AI Scientist (PhD or MSc in related field) → Molecular Modeler (PhD or 3+ years of experience)

#NewPaper published in ChemCatChem! This is how we engineered a bacterial peroxygenase (tyrosine hydroxylase) to expand its substrate scope, boosting its potential as a bacterial unspecific peroxygenase (BUPO). Proud to have participated in this study with scientists from GECCO Biotech, University of Groningen, Università di Pavia and Zymvol Biomodeling. Congrats to all the authors: Davide Carraretto, Lur Alonso Cotchico, Caterina Martin, Milos Trajkovic, Hugo van Beek, Andrea Matevi, Marco Fraaije, Maria Fátima Lucas and Nikola Lončar. Paper: https://lnkd.in/d9ZxWJxh #EnzymeEngineering #BUPO

Last week, as part of the BioInspireSensing outreach initiative, Jillian Gamboa, Ahammed Hussain Madhani Mohammed Sadhakathullah, Hamidreza Enshaei, Joan Torras-Costa from Universitat Politècnica de Catalunya and I from Zymvol Biomodeling had the privilege of engaging with school students at UPC Barcelona East School of Engineering. The session was a wonderful opportunity to spark curiosity and introduce these bright young minds to the transformative potential of bio-sensing. We kicked things off with an interactive presentation, sharing examples of everyday sensing devices and showcasing how innovations in this field are shaping the future of healthcare. To deepen their understanding, we engaged the students in two hands-on activities. One of the highlights was an experiment where they created a hydrogel to function as a simple pressure sensor. Seeing their excitement as they experimented and grasped the concept was truly inspiring! We also organized a questionnaire-based treasure hunt, where students explored 11 posters highlighting the contributions of early-stage researchers within our research network. Each poster offered a glimpse into their unique work, breaking down complex research into accessible and relatable insights. Their curiosity and enthusiasm reminded us of the importance of outreach activities like this—not only to share knowledge but also to inspire the next generation of researchers and innovators. #Outreach #BioInspireSensing #STEMEducation #FutureResearchers #MarieCurieActions #EuropeanCommision

#HIRING We're looking for a Junior #LabScientist to help us in the biocatalytical experimental execution of internal developments. 📌 Apply to our Junior Lab Scientists role to... → Perform multiple molecular biology experiments, including bacterial cell culturing, enzyme expression and purification. → Provide technical assistance in biocatalysis reaction screening. → Document and communicate the experimental results in a clear and organized manner. More details about the offer at Zymvol Careers (https://lnkd.in/ez-hzFn). 💡 About Zymvol At Zymvol we're a biotech company catalyzing change through enzyme innovation, helping key players meet sustainability standards and solve their biocatalysis challenges. Want to join the team? Check out the list of all our current job openings.

Have you met Gilberto Pereira and Laura Tiessler Sala? They’re two of our newest Senior Scientists, thanks to the #TorresQuevedo project. During their stay at Zymvol... 🥤 Gilberto will be investigating the interactions and efficacy of enzyme-functionalized surfaces for #PlasticDegradation. 🤖 Laura will be developing a new #AI based pipeline to design de novo BUPOs (Bacterial unspecific peroxygenases) for industrial applications. Welcome to the team! #TeamZymvol

Hace unas semanas tuve el placer de conversar con Maria Fátima Lucas, CEO de Zymvol Biomodeling y una destacada investigadora en química computacional. Fátima nos comparte su fascinante trayectoria desde sus inicios en la química hasta convertirse en una emprendedora exitosa en el mundo de la #biotecnología. 🔬 ¿Cómo comenzó su viaje?: Fátima nos cuenta que, aunque inicialmente se interesó por la biología, fue la química la que la atrapó desde joven. Su pasión por entender los procesos a nivel molecular la llevó a especializarse en bioquímica y finalmente a realizar su doctorado en química computacional. 💡 Desafíos en un mundo dominado por hombres: A lo largo de la conversación, Fátima reflexiona sobre las dificultades que enfrentan las mujeres en campos como la química computacional y el emprendimiento. A pesar de ser una minoría, ella nunca se sintió limitada por su género. Sin embargo, reconoce la importancia de visibilizar y fomentar la participación femenina en estos sectores. 🚀 Emprendiendo en biotecnología: Fátima comparte cómo su experiencia en el Barcelona Supercomputing Center la preparó para dar el salto al mundo empresarial. La creación de Zymvol fue impulsada por la necesidad de aplicar su conocimiento científico a soluciones prácticas en la industria. 🌍 Mirando hacia el futuro: Fátima también nos habla sobre su nueva aventura con OXYCO The Enzyme Factory, una empresa centrada en la producción de melanina, y cómo la innovación constante es clave para el éxito en el sector biotecnológico. ✨ Consejo para futuros emprendedores: Si pudiera hablar con su yo del pasado, Fátima le aconsejaría: "¡Haz un MBA mientras realizas tu postdoctorado! Tener conocimientos de negocio puede transformar tu carrera como investigador." 🔗 ¡No te pierdas esta inspiradora conversación! Escucha el episodio completo y descubre cómo la ciencia y el emprendimiento pueden cambiar el mundo: https://lnkd.in/dwaXAUBG #Emprendimiento #Ciencia #MujeresEnCiencia #Innovación #Podcast

🤔 How does the future of biomanufacturing looks like? Take a look at the latest post from Hack Summit to see a list of companies transforming manufacturing, bioengineering, and food production 🏭 🔬 Proud to see Zymvol Biomodeling recognized among the companies leading this wave of change for a more sustainable future.🌍 💚 #sustainability #biomanufacturing #biofuture #deeptech #biocatalysis #enzymes #greeninnovation https://lnkd.in/dtxepsRF

Monday I had the opportunity to present at #Biocat4Value how the combined use of Artificial Intelligence + Molecular Modeling + Bioinformatics is disrupting the Enzyme Engineering landscape. My take is… There will come a time when using AI only might be sufficient for any successful enzyme engineering campaign. But good quality data will always be needed, particularly for novel chemistry. As for now, my bet is on AI + Molecular Modeling leading the future. If there's something we've seen at work, it's that when you couple AI with physics-based simulations, you can generate high quality data and reduce the number of rounds of enzyme evolution. Spending less time Less resources But providing, nonetheless, reliable results.

Breaking an enzyme engineering dogma! It’s often said that improving an enzyme’s thermostability comes at the cost of activity (and vice versa). But we are challenging this notion. In our daily work, when improving an enzyme for performance, we are normally able to maintain (if not improve) stability. How? Long range mutations! In our latest work with the Stratingh Institute for Chemistry (University of Groningen), we show their importance and how boosting stability doesn’t have to mean sacrificing catalytic performance.

A while back, we were lucky to collaborate together with the Stratingh Institute for Chemistry (University of Groningen) on a study that could prove the importance of #ProteinDynamics in catalysis. The idea was simple: to further improve the catalytic performance of an already engineered enzyme by targeting distal mutations that affect the conformational equilibrium of the protein. Now, we’ve summarized the key findings from the original reserch paper in our latest case study. Check it out: