3-Metilbutanska kiselina

3-Metilbutanska kiselina
	3-Metilbutanska kiselina
Drugi nazivi	Delfinska kiselina; 3-Metilbuterna kiselina; Izopentanska kiselina
Identifikacija
CAS registarski broj	503-74-2
PubChem	10430
ChemSpider	10001
UNII	1BR7X184L5
DrugBank	DB03750
KEGG	C08262
ChEBI	28484
ChEMBL	CHEMBL568737
Jmol-3D slike	Slika 1
SMILES
	O=C(O)CC(C)C
InChI
	InChI=1S/C5H10O2/c1-4(2)3-5(6)7/h4H,3H2,1-2H3,(H,6,7) ; Kod: GWYFCOCPABKNJV-UHFFFAOYSA-N InChI=1/C5H10O2/c1-4(2)3-5(6)7/h4H,3H2,1-2H3,(H,6,7); Kod: GWYFCOCPABKNJV-UHFFFAOYAV
Svojstva
Molekulska formula	C5H10O2
Molarna masa	102,13 g/mol
Gustina	0,925 g/cm3
Tačka topljenja	-29 °C, 244 K, -20 °F
Tačka ključanja	175–177 °C
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

3-Metilbutanska kiselina (izovalerinska kiselina, delfinska kiselina, 3-metilbuterna kiselina, izopentanska kiselina) je prirodna masna kiselina, koja je prisutna u širokom nizu različitih biljki i esencijalnih ulja. Ona je prozirna, bezbojna tečnost, koja je umereno rastvorna u vodi, i ekstremno rastvorna u organskim rastvaračima.

Izovalerinska kiselina ima jak oporni miris sira ili znoja, dok njeni isparljivi estri imaju prijatne mirise i u širokoj su upotrebi u proizvodnji perfema. Po jednoj hipotezi ona je antikonvulzivni agens iz odoljena.^[6] Ona je glavna komponenta neprijatnog mirisa stopala^[7] koji formiraju bakterije kože kao proizvod metabolizma leucina. Izovalerinska daje ustajalom hmelju njegovu karakterističnu aromu i ukus.

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Eadie, Mervyn J (2004-11-01). „Could Valerian Have Been the First Anticonvulsant?”. Epilepsia 45 (11): 1338–1343. DOI:10.1111/j.0013-9580.2004.27904.x. ISSN 1528-1167. Pristupljeno 2012-05-09.
↑ Ara, Katsutoshi; Masakatsu Hama, Syunichi Akiba, Kenzo Koike, Koichi Okisaka, Toyoki Hagura, Tetsuro Kamiya, Fusao Tomita (2006-04-01). „Foot odor due to microbial metabolism and its control”. Canadian Journal of Microbiology 52 (4): 357–364. DOI:10.1139/w05-130. ISSN 0008-4166. PMID 16699586. Pristupljeno 2012-05-09.

Povezano

Izovalerinska acidemija

Vanjske veze

Portal Hemija

PubChem 10430

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[5] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[6] Eadie, Mervyn J (2004-11-01). „Could Valerian Have Been the First Anticonvulsant?”. Epilepsia 45 (11): 1338–1343. DOI:10.1111/j.0013-9580.2004.27904.x. ISSN 1528-1167. Pristupljeno 2012-05-09.

[7] Ara, Katsutoshi; Masakatsu Hama, Syunichi Akiba, Kenzo Koike, Koichi Okisaka, Toyoki Hagura, Tetsuro Kamiya, Fusao Tomita (2006-04-01). „Foot odor due to microbial metabolism and its control”. Canadian Journal of Microbiology 52 (4): 357–364. DOI:10.1139/w05-130. ISSN 0008-4166. PMID 16699586. Pristupljeno 2012-05-09.

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