Lab4Paws’ Post

Must-Read Research! Explore how a broken heart can be healed! Scientists from UBC, Borea Therapeutics, and Aspect Biosystems have uncovered region-specific mechanisms driving #heart repair after a #heartattack using 10x Genomics #Visium, advancing #therapeutic #angiogenesis strategies. Learn more: https://zurl.co/9XPCz

What makes Aqtual different?   Our efficient, single-analyte platform is the first of its kind to measure regulatory active chromatin. This approach enables us to identify an entirely new category of organ-specific DNA signatures. Evaluating protein regulation, epigenetics, and transcriptomics through a routine blood test offers new clinical applications in almost every major disease area. Learn more about our technology: https://lnkd.in/ef_Jyree #fAqtual #Aqtual #RA #ChronicConditions

The 𝟲𝘁𝗵 𝗠𝗮𝗰𝗿𝗼𝗽𝗵𝗮𝗴𝗲-𝗗𝗶𝗿𝗲𝗰𝘁𝗲𝗱 𝗧𝗵𝗲𝗿𝗮𝗽𝗶𝗲𝘀 𝗦𝘂𝗺𝗺𝗶𝘁 is finally kicking off tomorrow morning! We're proud to be the 𝗼𝗻𝗹𝘆 𝗲𝘃𝗲𝗻𝘁 uniting biopharma and academia to overcome the most pressing challenges in macrophage therapy research.   If you're in Boston currently, why not call in?   Tomorrow's workshop content will cover: 🔸𝗠𝗮𝗰𝗿𝗼𝗽𝗵𝗮𝗴𝗲 𝗕𝗶𝗼𝗹𝗼𝗴𝘆: Tackling terminology and categorization inconsistencies 🔸𝗗𝗶𝘃𝗲𝗿𝘀𝗲 𝗠𝗼𝗱𝗲𝗹𝘀: Assessing their suitability for different macrophage therapies 🔸𝗠𝗮𝗻𝘂𝗳𝗮𝗰𝘁𝘂𝗿𝗶𝗻𝗴 𝗖𝗵𝗮𝗹𝗹𝗲𝗻𝗴𝗲𝘀: Outlining cell sources and optimizing methods   𝗬𝗼𝘂 𝗰𝗮𝗻 𝗿𝗲𝗴𝗶𝘀𝘁𝗲𝗿 𝗮𝘁 𝘁𝗵𝗲 𝗱𝗼𝗼𝗿 𝗼𝗿 𝗼𝗻𝗹𝗶𝗻𝗲 𝗵𝗲𝗿𝗲 - https://ter.li/f31uj5   #MacrophageDirectedTherapiesSummit

Reviewing ten years of research on extracellular vesicle-associated DNA: Thupten Tsering, Julia V. Burnier at McGill University and collaborators explored the mechanisms of EV-DNA release, its biomarker potential, functional roles, conflicting findings in the field, and the challenges impeding its clinical application https://lnkd.in/eskD_8x2 The authors anticipate that advances in EV isolation and detection methods, along with better standardisation and data sharing, will drive the development of innovative strategies leveraging EV-DNA as a source of biomarkers and therapeutic targets. An article co-authored by Amélie Nadeau, Tad Wu and Kyle Dickinson #extracellularvesicles #exosomes #biomarkers #cellbiology #Vesiculab

Did you know that ABclonal’s Bax Rabbit mAb (A19684) has been cited in over 118 studies and validated for its specificity using Bax knockout (KO) 293T cells? This antibody plays a crucial role in apoptosis and cellular stress research, helping scientists better understand the mechanisms of cell death. If you're investigating apoptosis pathways or studying Bax protein expression, this antibody is a super reliable tool for your experiments. Feel free to explore more about the applications of Bax Rabbit mAb and how it could be useful in your research. https://hubs.li/Q02Rz6V10 #ApoptosisResearch #BaxAntibody #LifeSciences #CellularStress #ScientificResearch #ABclonal #AntibodyValidation #ResearchTools

#RNA plays a crucial role in biology and is a powerful tool in modern medicine. At Elixirgen Therapeutics, we are reimagining the power of RNA to develop various technologies for the treatment of #RareDiseases. Learn more here: https://bit.ly/3MZIFVK

I am thrilled to announce that our review paper on "Engineering Circular RNA for Molecular and Metabolic Reprogramming" has been published!🎉 In this review, we explore: 🔬 the promising applications of circular RNAs (circRNAs) in diagnostics, highlighting their potential use as biomarkers and therapeutic molecules. 🧬Advances in delivery systems and gene-editing technologies, bringing us closer to harnessing their full therapeutic potential. 💡However, to fully utilize circRNAs in various disease contexts, further research and extensive clinical studies are necessary. This paper marks a significant step forward in understanding and leveraging circRNAs for future medical applications. click the link below if interested to read further: https://lnkd.in/djeURPVc #CircularRNA #Biomarkers #Therapeutics #GeneEditing #CRISPR #BiomedicalResearch

Very interestin review highlighting not only DNA in EVs but also mecanism of secretion!

Molecular Regulators: Exploring Aladdin's Activin and Inhibin Pathways 🔬 Explore the cornerstone of scientific advancement with Aladdin Biochemical Reagent Company's Activin and Inhibin products! 🌟 Activin and Inhibin are not just proteins; they are essential players in understanding the intricacies of cellular signaling pathways, pivotal for groundbreaking scientific research and drug discovery. From deciphering developmental processes to uncovering potential therapies for diseases like cancer and infertility, Activin and Inhibin hold the key to unlocking new frontiers in biomedical science. Trust Aladdin for premium-grade reagents that fuel innovation and drive progress. Elevate your research today! #AladdinBiochemical #Activin #Inhibin #ScientificResearch #DrugDiscovery #AladdinScientific Aladdin：https://lnkd.in/g6qsm44R

Exciting news! 🎉We are thrilled to announce that Esya Labs has partnered with Alamar Biosciences to advance biomarker detection and diagnostics for neurological diseases like Alzheimer’s, Parkinson’s, and ALS. This collaboration combines ESYA's cutting-edge lysosomal biology and machine learning with Alamar’s ultra-sensitive #NULISA technology to revolutionize precision medicine. Now as an Alamar Certified Service Provider, ESYA Labs offers pharmaceutical companies access to cutting-edge tools that will improve the diagnosis and treatment of neurodegenerative diseases. 🚀 Read more about this transformative partnership here 👉 https://ow.ly/JyZc50Ul4Vo #proteomics #Biomarkers #NeurodegenerativeDiseases #PrecisionMedicine