Crinetics Pharmaceuticals’ Post

🖊️Abciximab Summary. Abciximab is a platelet aggregation inhibitor mainly used during and after coronary artery procedures like angioplasty to prevent platelets from sticking together and causing thrombus formation within coronary arteries. Abciximab works as a glycoprotein IIb/IIIa inhibitor. 🛒Brand: ReoPro The most common type of bleeding due to abciximab use is GI hemorrhage. It has a very short half-life - about 10 minutes - but its effects on platelet function can be seen for up to 48 hours after the infusion. Low levels of glycoprotein IIb/IIIa receptor blockade are present for up to 15 days post-infusion. #naplex

FDA Approves, the 1st and only, ready to use, Vabysmo PFS for 3 Leading Causes of Vision Loss Jul 8, 2024 They include Wet, or neovascular, age-related macular degeneration (AMD), diabetic macular edema (DME), and macular edema following retinal vein occlusion (RVO). Vabysmo (faricimab-svoa - Genetech) is the first bispecific antibody.  It targets and inhibits two signaling pathways linked to a number of vision-threatening retinal conditions by neutralizing angiopoietin-2 (Ang-2) and vascular endothelial growth factor-A (VEGF-A). Ang-2 and VEGF-A are thought to contribute to vision loss by destabilizing blood vessels. It may cause new leaky blood vessels to form and increase inflammation. By blocking pathways involving Ang-2 and VEGF-A, Vabysmo is designed to stabilize blood vessels. #visionloss #agerelatedmaculardegeneration #diabeticmacularedema #researchanddevelopment #innovation #pfs #healthcare #lifesciences #innovation #fdaapproval #monoclonalantibody #qualityoflife

Common Adverse Reactions to EGFR Therapy: Alan Chin, PharmD, BCOP, presents an overview of the most prevalent and common adverse reactions associated with EGFR-targeted therapies in metastatic NSCLC and shares strategies to mitigate toxicities, with a focus on managing dermatologic events such as rash and itching. #finance #pharmacy #lifesciences

Tired of relying on medications for pain relief? Gladiator Therapeutics offers a drug-free alternative. By utilizing far infrared light, our patented devices stimulate blood flow and decrease inflammation naturally, offering a gentle yet effective solution for managing pain without the side effects of prescriptions. https://ow.ly/gLwl50REyBG #GladiatorTherapeutics #FIR #Pain #PainManagement #DrugFree #AlternativeMedicine #ActiveHealing

Statins remain the cornerstone of therapy for lowering LDL-C. For patients requiring additional LDL-C reduction, adjunctive options such as ezetimibe, PCSK9 inhibitors, and bempedoic acid offer further therapeutic strategies. Explore these avenues to optimize your patients' lipid management. #hearthealth #LearnYourLipids #HeartMonth

Empower Lives with Deflamax: A Breakthrough in Duchenne Muscular Dystrophy Treatment! We #General_Pharmaceuticals_Ltd introducing our new generic drug #Deflamax (Deflazacort 6mg and 24 mg Tablets) for managing muscle inflammatory conditions like Duchenne Muscular Dystrophy. It is one of the safe steroids that can ensure the safety from other side-effects. What is #Deflazacort? Deflazacort is a corticosteroid medication specifically designed to treat Duchenne muscular dystrophy in both adults and children aged 2 years and older. This condition leads to progressive muscle weakness, but Deflazacort can help improve muscle strength and slow the progression of disability. #Reduces_Inflammation: Helps manage the symptoms of DMD by reducing inflammation. #Improves_Muscle_Strength: Enhances muscle function and slows down muscle degeneration. #FDA_Approved: Recognized and approved by the FDA for its efficacy and safety. For more Information: www.generalpharma.com For any Queries or Information: emon.imd@generalpharma.com What'sApp Contact: +8801825449339 Want to learn more about Deflazacort and its benefits? Connect with us and discover how this medication can transform lives. #Deflamax #Deflazacort #GPL_IMD #Export

Ophthopedia Update:Evaluating the Efficacy and Safety of Aflibercept Biosimilar (P041) Compared to Originator Product in Patients with Neovascular Age-related Macular Degeneration: To assess the non-inferiority of biosimilar aflibercept (CinnaGen Company, Iran) (P041) to the originator aflibercept (Regeneron, US) (AFL) in terms of efficacy, safety, and immunogenicity. #Ophthalmology #Retina #Ophthotwitter

"The BBB is vital for the brain, but its presence calls for novel and creative approaches for treating CNS diseases and CNS metastases. " "Drug delivery strategies (polymeric microparticles, nanoemulsions, liposomes etc.) are constantly advancing and evolving, presenting the possibility of delivering new therapeutic agents like TPDs across the BBB." from Prashant Agarwal et al. Prashant Agarwal, Darren Reid, and Mansoor Amiji. "CNS delivery of targeted protein degraders." Journal of Controlled Release 372 (2024): 661-673. #CNS #proteindegraders #drugdelivery #BBB #formulations Keywords: Targeted protein degraders Physicochemical properties CNS delivery Blood-brain barrier Formulations strategies

Fast-Track Your Recovery with #PeptideTherapy. As an athlete, staying active and in top shape is crucial. But when injuries strike, getting back to 100% can feel like an uphill battle. Our bodies are incredible at healing naturally, but let’s be real—it’s not always a quick process. ✅ The great news? #Peptide therapy can supercharge your recovery and get you back to peak performance FAST. 💪 💡 You’ve heard of #BPC157 & #TB500, but let me introduce you to my latest obsession: #Regenovive—the quantum-healing PEPTIDE BIOREGULATOR cream that’s revolutionizing the game. 🧬🔥 Want to learn more about the best peptides (and peptide bioregulator cream) for pain relief and #InjuryRecovery? ➡️ Check out my latest blog post: https://lnkd.in/e_Di3D9f 💬 What’s your go-to strategy for a speedy recovery? 👇🏻

🚨 Big News in #ObesityMedicine! Structure Therapeutics just dosed the first patients in their trial for GSBR-1290, an oral GLP-1 receptor agonist that could change the game for obesity and type 2 diabetes treatment. 🌐 No needles, no refrigeration—just a once-daily pill that aims to deliver the same benefits as injectable meds like Ozempic and Mounjaro. Are oral GLP-1s the future of weight loss meds? 💊 We break down the details and what this means for the next generation of #GLP1 treatments on On The Pen. 👉 Read more at https://wix.to/2nDNYQV #OnThePen #GLP1 #ObesityMedicine