Inherited Cancer Registry (ICARE)

Are you considering getting tested for inherited cancer? We provide free education about inherited cancer risk through our Tool for Inherited Cancer Predisposition Counseling and Testing Study (TIPS).   Visit https://redcap.link/TIPS and complete our survey. Once completed, we provide: • an automatically generated drawing of your family tree • an assessment to tell you if you are at high risk for having inherited cancer    Join today to receive free education and assessment about inherited cancer risk!   #ICARE #InheritedCancerRegistry #InheritedCancer #HereditaryCancer #Cancer #CancerGenetics #GeneticTesting #CancerRisks #CancerRiskManagement #RiskAssessment #CancerPrevention #CancerResearch #Education #GeneticCounseling #GCchat #CancerAwareness

A recent study found that among women with BRCA1 and BRCA2 mutations, oral contraceptive use:  🧬 Increased risk of breast cancer with proportionate increases of 3% for each year of hormonal contraceptive use among BRCA1 carriers.   🧬 No association seen for BRCA2 carriers. 📈 Why is this important? • It would be important to discuss this information with young BRCA1 carriers as they make choices about contraception and preventive removal of the ovaries and fallopian tubes. Read the full article to learn more at: https://lnkd.in/edg62ndx Reference: Phillips, et al. J Clin Oncol. 2024:JCO2400176. PMID: 39356978. #ICARE #InheritedCancerRegistry #InheritedCancer #HereditaryCancer #Cancer #BreastCancer #BreastCancerRisk #HereditaryBreastCancer #OvarianCancer #OvarianCancerRisk #OralContraceptives #BirthControl #CancerGenetics #GeneticTesting #BRCA #BRCA1 #BRCA2 #CancerRisks #CancerRiskManagement #CancerPrevention #CancerScreening #CancerRiskReduction

If you have a history of breast cancer and a mutation in the CHEK2 gene, you may be eligible to contribute to tumor genomics studies to help better understand inherited breast cancer in CHEK2 carriers. Through the Inherited Cancer Registry (ICARE), we are studying: - breast cancer characteristics - factors associated with outcomes, including treatments - tumor genomics to better understand pathways to tumor development With your help, we hope that one day our research may lead to new or refined treatment strategies! To learn more about participating in ICARE or if you'd like to enroll online, please visit https://lnkd.in/g9Xn6jZ. Once you are enrolled into ICARE, our research team will assess your eligibility for this and other focused research efforts. #ICARE #InheritedCancerRegistry #InheritedCancer #HereditaryCancer #Cancer #BreastCancer #InheritedBreastCancer #HBOC #CHEK2 #CancerGenetics #GeneticTesting #Genomics #TumorTesting #TumorGenomics #CancerRisks #CancerRiskManagement #CancerPrevention #CancerResearch #CancerTreatment 

Did you know that inherited cancer gene mutations in TP53, RB1, NF1, APC, KIT, and PDGFR can raise the risk for certain sarcomas? In fact, one in ten people with osteosarcoma have an inherited cancer risk gene mutation. If you are a sarcoma patient, you may want to consider genetic testing. We ask that you also consider joining our CAUSAL study through which we trying to learn more about sarcoma patients. No travel to our center is needed, and everything can be done online. Participating in this study involves taking surveys, monitoring your physical activity with a free Fitbit, free genetic testing for inherited cancer, and free tumor testing. Your participation could help develop new ways to improve cancer treatment and quality of life as well as to learn more about sarcoma causes and prevention.   To learn more about participating, please visit https://lnkd.in/eXEPh7JB   #ICARE #InheritedCancer #HereditaryCancer #Cancer #Sarcoma #CancerResearch #CAUSAL #GeneticTesting #TP53 #RB1 #NF1 #APC #KIT #PDGFR #CancerGenomics #CancerRisks #CancerPrevention

Why have genetic testing? Genetic testing for inherited cancer can help guide care, including:  • Cancer treatment plans, such as chemotherapy, drugs, surgery, and radiation  • Cancer screening and prevention Sharing genetic test results can also help family members understand their cancer risks. ⁠ #ICARE #InheritedCancerRegistry #InheritedCancer #HereditaryCancer #Cancer #CancerGenetics #GeneticTesting #CancerRisks #CancerRiskManagement #RiskAssessment #CancerPrevention #CancerResearch #Education #GeneticCounseling #CancerAwareness American Society of Clinical Oncology (ASCO) American Cancer Society National Cancer Institute (NCI) Vanderbilt Health Vanderbilt-Ingram Cancer

If you have a history of breast cancer and a mutation in the BRCA1 and/or BRCA2 genes, you may be eligible to contribute to tumor genomics studies to help better understand inherited breast cancer in BRCA1/2 carriers. Through the Inherited Cancer Registry (ICARE), we are studying: - breast cancer characteristics - factors associated with outcomes, including treatments - tumor genomics to better understand pathways to tumor development With your help, we hope that one day our research may lead to new or refined treatment strategies! To learn more about participating in ICARE or if you'd like to enroll online, please visit https://lnkd.in/g9Xn6jZ. Once you are enrolled into ICARE, our research team will assess your eligibility for this and other focused research efforts. #ICARE #InheritedCancerRegistry #InheritedCancer #HereditaryCancer #Cancer #BreastCancer #InheritedBreastCancer #HBOC #BRCA #BRCA1 #BRCA2 #CancerGenetics #GeneticTesting #Genomics #TumorTesting #TumorGenomics #CancerRisks #CancerRiskManagement #CancerPrevention #CancerResearch #CancerTreatment 

Visit our YouTube channel at the link below to watch an exciting presentation from yesterday's ICARE Genetics Case Conference, during which Lora Thompson, PhD from Moffitt Cancer Center discusses coping with hereditary cancer 🧬 ⤸ https://lnkd.in/gvvPGWBD Dr. Thompson was joined in commentary by BRCA carriers, Marleah Dean Kruzel, PhD (University of South Florida) and Kathy Baker (My Faulty Gene), as well as panelists Deborah Cragun, PhD, MS, CGC (University of South Florida) and Kelly Metcalfe, RN, PhD (University of Toronto). If you would like to watch the recording of the entire conference, including discussion, please visit ⤸ https://lnkd.in/gxA4pHmp #ICARE #InheritedCancerRegistry #InheritedCancer #HereditaryCancer #Cancer #Genetics #CancerGenetics #BRCA #BRCA1 #BRCA2 #CancerGenomics #GeneticTesting #CancerRisks #GeneticsWebinar #CancerEducation 

Please consider joining our study at https://lnkd.in/gFyR5Tpr if you have an inherited breast cancer gene mutation. In those with a breast cancer diagnosis, we are doing free genomic testing on tumor samples to better understand inherited breast cancers. Once you enroll in our study, we will assess your eligibility for this and other focused research efforts.   #ICARE #InheritedCancerRegistry #InheritedCancer #HereditaryCancer #Cancer #BreastCancer #BRCA1 #BRCA2 #BRCA #PALB2 #ATM #CHEK2 #CancerGenetics #GeneticTesting #Genomics #CancerGenomics #TumorTesting #CancerRisks #CancerRiskManagement #CancerPrevention #CancerResearch #CancerTreatment

A new international study in over 8000 BRCA1/2 carriers, including ICARE participants, showed lifetime pancreatic cancer risk to age 80 in: • BRCA1 was 2.2% (95% CI: 1.1%-4.3%) • BRCA2 was 2.7% (95% CI: 1.3%-5.2%)   👩👩👧👦 Of the 34 BRCA carriers with pancreatic cancer, 2 reported a first-degree relative with pancreatic cancer.    ⚠️ Risk factors for pancreatic cancer include alcohol intake and history of diabetes.   📈 5-year survival rate for the 34 BRCA carriers with pancreatic cancer was 8.8%, which highlights the need to develop strategies for prevention and early detection! Read the full article to learn more at: https://lnkd.in/g4HQBVvv Reference: Katona, et al. Cancer. 2024. Online ahead of print. PMID: 39611336. #ICARE #InheritedCancerRegistry #InheritedCancer #HereditaryCancer #Cancer #PancreaticCancer #BRCA #BRCA1 #BRCA2 #CancerRisks #CancerGenetics #GeneticTesting #CancerPrevention #CancerAwareness

We hope you will attend our next ICARE Genetics Case Conference, on Thursday, December 12th from 11:30am - 12:30pm CT, focused on Coping with Hereditary Cancer with presentation by Lora Thompson, PhD from the Moffitt Cancer Center. Dr. Thompson will be joined in commentary by BRCA carriers, Marleah Kruzel, PhD (University of South Florida) and Kathy Baker (My Faulty Gene), and panelists Deborah Cragun, PhD, MS, CGC (University of South Florida) and Kelly Metcalfe, RN, PhD (University of Toronto).   We encourage you to join us for this exciting conference which is broadly accessible. Please register using the link below. After registering, you will receive a confirmation email containing instructions on how to join the conference at the scheduled time.   https://lnkd.in/eXB2qEEg #ICARE #InheritedCancerRegistry #InheritedCancer #HereditaryCancer #Cancer #CancerGenetics #GeneticTesting #CancerRisks #CancerRiskManagement #CancerPrevention #GeneticsWebinar #GeneticsEducation #CancerEducation