Proactive

Prescient Therapeutics jumped as much as 53.7% this morning after receiving a green light from the US FDA to proceed with its Phase 2 clinical trial of PTX-100 — the company’s first-in-class Ras pathway inhibitor.  The FDA cleared the Investigational New Drug (IND) application for the Phase 2 trial 100 — a significant milestone for Prescient — paving the way for the commencement of the Phase 2 study which will focus on relapsed and refractory cutaneous T-cell lymphomas (r/r CTCL).  The planned Phase 2 study builds on compelling Phase 1b data that demonstrated PTX-100’s potential to address key unmet medical needs in T-cell lymphomas (TCL), including r/r CTCL.  More at #Proactive #ProactiveInvestors #Prescient #CTCL #ASX #PTX #PSTTF #ASXbiotech #lymphomas #Tcell http://ow.ly/j8rS105SkYf

Wedgemount Resources Corp (CSE:WDGY, OTCQB:WDGRF) CEO Mark Vanry joined Proactive to discuss significant achievements from the company in 2024 and its outlook for the New Year. He highlighted the Huggy acquisition, which has quadrupled Wedgemount’s operational scale. Proactive: The company recently issued a news release highlighting 2024 milestones and looking ahead to 2025. Let’s start with west-central Texas and your oil and gas assets there. What’s happening in that region? Mark Vanry: In August, we made our largest acquisition to date: the Huggy acquisition. It quadrupled the size of our company. Since closing that deal, our focus has been on optimizing... http://ow.ly/z6bh105SgLs

Alvopetro Energy Ltd (TSX-V:ALV, OTC:ALVOF) CEO Corey Ruttan talked with Proactive about the company’s 2024 performance and strategic goals. Ruttan detailed the company’s November production numbers, which reflected seasonal maintenance by both Alvopetro and its gas consumers. This led to a temporary dip, but December’s production rebounded significantly, increasing by 43%. Proactive: Let’s start with November. You've updated your sales numbers. There were some interesting numbers in there. Corey Ruttan: Yes, we announce our production monthly. November was a bit lower. In the state where we produce gas, November is typically a time for facility maintenance... http://ow.ly/FFYB105Sgyy

First Phosphate Corp. (CSE:PHOS, OTCQB:FRSPF) earlier this week announced key developments that strengthen its position as a resource developer. The company signed offtake agreements for upstream phosphate processing, which it said enhance the financial viability of its operations and pave the way for future feasibility studies. CEO John Passalacqua highlighted the agreements as a significant achievement for the company’s size and stage of development, crediting the quality of its Preliminary Economic Assessment (PEA) and resources at Bégin-Lamarche. The company also announced progress in its collaboration with First Nations partners. It signed an agreement... http://ow.ly/ejHA105SghH

NEXE Innovations Inc (TSX-V:NEXE, OTC:NEXNF) president Ash Guglani talked with Proactive about the company’s growing partnership with EKOCUPS, a major US-based Amazon seller. He emphasized that this collaboration marks a significant step for Nexe as it strengthens its recurring revenue in the US coffee capsule market. Proactive: So, another news release from the company today talking about more recurring business. As far as this company called EKOCUPS that we've talked about in the past—this is really the pathway for the company into the US. Ash Guglani: Yeah, absolutely. Look, I mean, we have a good growing relationship with EKOCUPS know, they're giving us... http://ow.ly/zLB4105SgeA

Zero Candida Ltd (TSX-V:ZCT) is at the forefront of biotech innovation, addressing the growing need for effective solutions to combat fungal infections. In this Q&A, CEO Eli Ben Haroosh discusses their strategic vision, the technology driving their mission, and the market potential of their advancements in Candida treatment. Proactive: We’re going to talk about your company securing a patent in South Africa. But before we dive into that, can you tell us a bit more about Zero Candida and the work you’re doing? Eli Ben Haroosh: Of course. Our team has been doing amazing work. We’ve had a PhD consultant working with us for over five years, helping us develop and... http://ow.ly/2Fou105SfXi

EnWave Corp (TSX-V:ENW, OTC:NWVCF) CEO Brent Charleton spoke with Proactive about the company’s recent strides, including a partnership with ELEA Technology to develop healthier snacks, a strong rebound in 2024 financial performance, and a key board appointment. Charleton shared how these advancements, alongside EnWave’s patented REV drying technology, are shaping the company’s growth strategy for 2025 and beyond. Proactive: There’s been a lot of news over the last few days. First, you've announced a partnership with ELEA Technology. This is for healthier snacks. Tell me about how this came about. Brent Charleton: We previously explored combining their... http://ow.ly/iI2P105SbM0

Arizona Gold & Silver Inc (TSX-V:AZS, OTCQB:AZASF) CEO Mike Stark joined Proactive to discuss the company’s latest drill results from two key sites at its Philadelphia gold-silver project in Arizona, Red Hills and Rising Fawn. He highlighted that the drill holes at Red Hills have exceeded expectations with larger-than-anticipated widths, and geologists are optimistic about the findings at Rising Fawn. Proactive: Last time you and I chatted, you were on site witnessing the beginning of your drill program. Let’s start by talking about the two areas you’re focusing on in this program. Mike Stark: Very interesting areas. We’re extremely pleased right now. Two... http://ow.ly/ucrJ105Sfx1

European Green Transition's chief explains why its ambitions are broader than rare earths - ICYMI @EuropeanGreenT #AIM #EGT. European Green Transition PLC (AIM:EGT) chief executive Aiden Lavelle talks through the latest Olserum drill results and plans beyond exploring for rare earths. Aiden Lavelle: We've announced the results for another five holes [at Olserum] which makes a total of 13 across the Olserum West and Djupedal prospects at the project in South Sweden. And, again, all five holes that we announced this morning have hit mineralisation. We had two very good intersections. One of the holes at Djupedal intercepted 2.45m grading 2.71% total rare earth... http://ow.ly/v9V3105Sfj9

Giyani Metals CEO on progress at Johannesburg demo plant - ICYMI @GiyaniMetals #TSXV #OTC #EMM #CATPF. Giyani Metals Corp (TSX-V:EMM, OTC:CATPF) CEO Charles FitzRoy talked with Proactive about the commissioning progress of their demonstration plant in Johannesburg. While the company targets first production of high-purity manganese sulfate monohydrate this year, unforeseen setbacks like power and water outages have caused potential delays into early Q1. FitzRoy highlighted the plant's role in de-risking the main facility planned for Botswana and noted minor adjustments that improve operational insights. Proactive: Charlie, very good to speak with you. You're... http://ow.ly/EM91105Sfbx