Cancers MDPI

📢 Cancers MDPI was awarded an updated Impact Factor of 4.5 in the 2023 Journal Citation Reports released by Clarivate in June 2024. The journal rank has now been upgraded to JCR Q1 (78/322 in the 'Oncology' category, 5-Year Impact Factor: 4.9). 👉 Read more: https://lnkd.in/g7JUNySw

📜Today we share the #Review "HER2 positive Metastatic Breast Cancer: Available treatments and current developments" 👥by Ismail Essadi et al. Cadi Ayyad University Access the full paper here▶ https://lnkd.in/dJJNsBry Keywords: metastatic breast cancer; HER2-positive; targeted therapies

🏆Check out the Editor's Choice #Review "Heat Shock Proteins, a Double-Edged Sword: Significance in Cancer Progression, Chemotherapy Resistance and Novel Therapeutic Perspectives" ✍by Dominika Kunachowicz et al. Wroclaw Medical University 🔗Link here: https://lnkd.in/dHrSsQ9C 🔸This is a thorough review of the roles of heat shock proteins in cancer and in cancer drug resistance. It is particularly interesting, because it emphasises the complexity of the roles that heat shock proteins can play. Due to this, the review nicely illustrates why the design of effective cancer therapies is such a challenge and why future, individualised therapies will depend on an ever-increasing understanding of the minute detail of the underlying processes.🔸

🧐Check out the #Article "MicroRNA-483-5p Inhibits Hepatocellular Carcinoma Cell Proliferation, Cell Steatosis, and Fibrosis by Targeting PPARα and TIMP2" 👏by Suryakant Niture et al. North Carolina Central University Find out more here👉 https://lnkd.in/ddWwD8HM Keywords: miR-483-5p; NAFLD; AFLD

📜We share the #Review "Role and Potential of Different T Helper Cell Subsets in Adoptive Cell Therapy" 👥by David Andreu-Sanz and Sebastian Kobold LMU Klinikum München Linke here: https://lnkd.in/eadnawyY Keywords: adoptive cell therapy; CD4+ T cell; immunotherapy

🔊Today we share the #Article "5-Fluorouracil Suppresses Colon Tumor through Activating the p53-Fas Pathway to Sensitize Myeloid-Derived Suppressor Cells to FasL+ Cytotoxic T Lymphocyte Cytotoxicity" 🧐by Yingcui Yang et al. Tianjin University of Science & Technology Find out more here▶️ https://lnkd.in/dj-AAC52 Keywords: 5-FU; MDSCs; Fas

🏆Check out the Editor's Choice #Article "Current State of Melanoma Therapy and Next Steps: Battling Therapeutic Resistance" ✍by Anna Fateeva et al. Rutgers University–New Brunswick 🔗Link here: https://lnkd.in/dAzrBgsD 🔹This review provides a very nice overview of the recent improvements in treating melanomas but also of the challenges that are still lying ahead of us. It keeps a good balance between the progress that has been achieved for a substantial fraction of patients suffering from a disease for which no significant improvements had been achieved in a long time on the one hand and the reality that a majority of patients still cannot be satisfactorily treated on the other hand. In doing this, this review emphasises that progress in cancer treatments happens in small steps, and that we cannot ease off in our fight against the disease.🔹

🧐Check out the #Article "MVI-TR: A Transformer-Based Deep Learning Model with Contrast-Enhanced CT for Preoperative Prediction of Microvascular Invasion in Hepatocellular Carcinoma" 👥by Linping Cao et al. Zhejiang University 📌Find the full paper here: https://lnkd.in/dspcXjSe Keywords: microvascular invasion; transformer model; contrast-enhanced computed tomography

Members of the Surgical Outcomes Research Centre (SOuRCe) Team are guest-editing a special issue in Cancers MDPI on ‘Survivorship and Life with Colorectal Cancer’.   This issue brings together experts in colorectal cancer survivorship to facilitate dialogue that advances our understanding of post-treatment challenges, quality-of-life considerations, and innovative approaches to supporting the long-term health and wellbeing of survivors.   Manuscript submissions that contribute to this important discussion are warmly welcomed.   For more information, please see: https://lnkd.in/gGh6YmVE #cancer #QoL #wellbeing Sydney Local Health District RPA Institute of Academic Surgery University of Sydney Sydney Research