Takis

2024 was a transformative year for Takis! A standout was the opening of our new BSL-3 Facility, boosting our research capabilities. We've also made significant strides in monoclonal antibody production, with scaling techniques showcased at key venues like I4ID2024 in Lyon. Takis was also selected for the IPCEI "Med4Cure" project, focusing on vaccines and gene therapies, including developing treatments for COVID-19 and cancer. We've laid the groundwork for greater international presence, engaging with the U.S. and Chilean Embassies for cross-border collaborations. Nationally, we led Rome Technopole’s Flagship Project 7 alongside public and private institutions. Our COO, Emanuele Marra, joined the Pharmaceutical and Biomedical board of Unindustria, reflecting our influence in Italy’s industrial and scientific sectors. Finally, we even changed our logo! Heartfelt thanks to our clients, partners, collaborators, and supporters. Wishing everyone a joyous holiday season and a successful New Year!

As Christmas approaches, we gathered to have a little celebration and enjoy some time all together. Research doesn’t just happen in a lab. It is the result of effective teamwork. That’s why moments like this are so important! May this holiday season bring joy, warmth and inspiration to you and your families. Happy Holidays from all of us at Takis!

This week marked a special occasion at Takis as we celebrated Antonella Costanzo's successful Ph.D. defense, titled "Structural and functional characterization of a humanized neutralizing antibody targeting the SARS-CoV-2 Receptor Binding Domain (RBD)" at Sapienza Università di Roma. Guided by Dr. Carmelinda Savino, Dr. Giuseppe Roscilli (CTO of Takis), and Prof.ssa beatrice vallone, Antonella has contributed significantly to our monoclonal antibodies group. Her project focused on characterizing antibodies targeting the spike protein of SARS-CoV-2, generated by hybridoma technology. She shares: "The goal is to identify epitopes by resolving the Fab fragments' structure with the spike protein via cryo-electron microscopy (Cryo-EM). This understanding is crucial for optimizing antibody-antigen interactions." Her project explored also how SARS-CoV-2 variant mutations affect antibody recognition. With 9-8F2-B11's broad neutralization potential, it stands as an ideal candidate for engineering against new variants. We proudly support Antonella's growth and wish her continued success. Good luck, Antonella!

Meet Monica Fraternali, our dedicated Human Resources Manager! With a degree in Law, Monica Fraternali joined Takis in 2014 in the administrative office, specializing in financial reporting for funded projects. Over the years, Monica has seamlessly transitioned into the role of HR Manager, where she combine her strong administrative expertise with a solid legal background to craft people-centered strategies aligned with the company’s objectives. In this role, Monica excels in talent acquisition, employee development, and creating a positive work environment. Her efforts are crucial in enhancing employee satisfaction and driving overall company performance. We greatly appreciate Monica's commitment to fostering a thriving workplace and look forward to their continued impact at Takis!

Takis Invasive Aspergillosis Model: a way to fight invasive fungal infections. Aspergillus fumigatus is a common fungus that poses a serious threat to immunocompromised individuals, causing invasive pulmonary aspergillosis (IPA), a life-threatening infection that invades blood vessels. At Takis, we recognize the urgency of finding more effective treatments for IPA: to this end we have developed an advanced rodent model of IPA to evaluate new drug therapies and their combination with existing treatments. Our model is a crucial tool for testing antifungal drugs and exploring innovative combination therapies to improve patient outcomes. By supporting researchers and pharmaceutical companies, we are helping advance the fight against IPA and improving treatment options for vulnerable patients.

Where #Biotech “Magic” Happens: Turning Science into Breakthroughs! Our #laboratory is the beating heart of research, now enhanced with a BSL-3 facility. We are proud to work in the Tecnopolo Roma, together with other research institutes and biotech companies, with state-of-the-art equipment and workspaces designed for maximum efficiency. And why not enjoying our work and having some fun everyday as we work on collaborative projects? If you want to know more about us, follow our company page! Takis

Takis was honored to participate as both exhibitor and speaker at the 8th #Immunotherapies & #Innovations for Infectious #Diseases Congress (I4ID Congress), held on November 27th-28th in Lyon! We extend our gratitude to everyone who visited our booth, where laura luberto, Antonella Conforti, Alessia Muzi, and Giuseppe Roscilli shared Takis' latest groundbreaking research. An highlight for our team was Antonella Conforti's talk on “Development of novel genetic vaccine platforms for epidemic preparedness: from the idea to GMP production,” offering insights into our advancements in vaccine technology. This dynamic two-day congress gathered pharmaceutical leaders, research institutions, tech innovators, and clinicians to foster collaboration and drive innovation in the fight against infectious diseases. Beyond the inspiring scientific program, the event featured valuable networking opportunities, technology showcases, and an online B2B platform for business collaborations. We are proud to be part of such an inspiring event, driving innovation and #collaboration to combat infectious diseases and shape the future of #healthcare.

Explore the inside of our new #BSL3 module! This facility is equipped with state-of-the-art #technology and rigorous procedures, essential for testing #vaccines, #therapeutics, and #treatments against pathogens such as SARS-CoV-2, Mycobacterium tuberculosis and Dengue virus. Through the use of innovative filtration systems, intelligent safety adjustments, and strict protocols, the module provides a fully isolated environment from the outside world, ensuring the utmost #safety. The module is also fully transportable by truck or container, making it accessible for the use anywhere in the world. We are confident this facility will play a pivotal role in advancing epidemic preparedness and biomedical #innovation, becoming a key resource for Italian and European institutions that require a safe and reliable structure. The experience of COVID-19 showed the urgent need for facilities like this, and now Takis is proud to address this gap. If you want to know more, send us a message here on LinkedIn!

Meet Denise Svegliati, our talented Administrative Support Specialist! At 26, Denise is a university student pursuing a degree in Languages and Literature for Intercultural Communication. She joined Takis in May 2023 and has quickly become an integral part of our team. Denise wears many hats at Takis, excelling as our Administrative Support Specialist, Warehouse Manager, and Travel Organizer. Her sights are set on advancing into the role of Management Secretary, a goal she’s already working toward by skillfully managing schedules for our leadership team and coordinating company events. We deeply value Denise’s dedication and enthusiasm and look forward to supporting her continued growth with us!

Save the Date: November 27th-28th in Lyon! Join us at the 8th Immunotherapies & Innovations for Infectious Diseases Congress (I4ID Congress), where Takis will be present as an exhibitor and as speaker! We will have the booth number 7, where you will find our own laura luberto, Antonella Conforti, Alessia Muzi and Giuseppe Roscilli, ready to welcome you and share our latest research. We're also thrilled to announce that Antonella Conforti from Takis will deliver a talk on “Development of novel genetic vaccine platforms for epidemic preparedness: from the idea to GMP production,” sharing our advancements in vaccine development. This two-day congress brings together pharmaceutical industries, research labs, technology developers, and clinicians to foster #collaboration and #innovation in the fight against infectious #diseases. In addition to the scientific program, the event offers networking opportunities, a showcase for new technologies, and a dedicated online B2B platform for business partnering. Looking forward to connecting with industry peers and advancing the future of infectious disease #immunotherapy. See you in Lyon!