2-OH-NPA je lek koji se koristi u naučnim istraživanjima i koji deluje kao potentan i selektivan agonist za dopaminski D2 receptor.[4]
2-OH-NPA
|
| (IUPAC) ime
|
| (R)-2,10,11-trihidroksi-N-propilnoraporfin
|
| Klinički podaci
|
| Identifikatori
|
| CAS broj
|
79640-85-0
|
| ATC kod
|
?
|
| PubChem[1][2]
|
6603798
|
| ChemSpider[3]
|
8244599
|
| Hemijski podaci
|
| Formula
|
C19H21NO3
|
| Mol. masa
|
311,374 g/mol
|
| SMILES
|
eMolekuli & PubHem
|
| InChI |
|---|
InChI=1S/C19H21NO3.BrH/c1-2-6-20-7-5-12-8-13(21)10-14-17(12)15(20)9-11-3-4-16(22)19(23)18(11)14;/h3-4,8,10,15,21-23H,2,5-7,9H2,1H3;1H/t15-;/m1./s1  Y
Key: KIAIFHTWTMKEDI-XFULWGLBSA-N Y |
|
| Farmakoinformacioni podaci
|
| Trudnoća
|
?
|
| Pravni status
|
|
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
- ↑ Gao YG, Baldessarini RJ, Kula NS, Neumeyer JL (1990). „Synthesis and dopamine receptor affinities of enantiomers of 2-substituted apomorphines and their N-n-propyl analogues”. Journal of medicinal chemistry 33 (6): 1800–5. DOI:10.1021/jm00168a040. PMID 1971309.
