Regarding the NYT's piece on drug pricing

Reading the New York Times this morning, this piece caught my eye. I have a lot of respect for both reporters in the byline, especially their acknowledging that the way the U.S. pays for prescription drugs is complex and rife with perverse incentives.

While I understand the temptation to look outside the U.S. for answers, here are a few points that I wish had been reflected in the piece.

  • The U.S. is the R&D leader of the world, and there is a complex ecosystem of investors and payors. There are large costs – and risks – with bringing a molecule from the lab to a patient, and recent NPC research suggests that most of the cost of that risk is borne by drug developers. 
  • We are in a golden age of biopharmaceutical innovation. Last year, the FDA approved 55 novel drugs – the second-highest over the last 30 years. And U.S. patients typically have earlier access to newly launched products than patients in other countries with a single negotiator.
  • As a percentage, what we spend on drugs compared to overall health spending in the U.S. is one of the lowest of economically-similar countries. 
  • We already have price negotiation in the U.S. - currently done by commercial payers – and one need only look at the rise in formulary exclusions to dispel the myth that our health care system isn’t willing to negotiate hard.
  • Don’t forget: Because of the way we pay for medicines in the U.S., there are drug shortages for medicines with prices that are too low.

Finally, central planning and price regulation don’t lead to innovation. Adopting the practices of international systems that limit patient access isn’t likely to be the answer.  

Richard Parrish, DPh, PhD, FCCP, BCPS

Award-winning Pharmacist Clinician | Leader | Radical for children

11mo

Continued support for the Bayh-Dole Act of 1980 will keep the innovation engine running. https://en.m.wikipedia.org/wiki/Bayh–Dole_Act

Dean Hakanson MD

Chief Medical Officer

11mo

John, you bring a good perspective with these data points and it remains central to having a more balanced approach to these issues.

Virginia Acha

Focused on innovation policy that matters for people and the planet * Science & Regulatory policy global executive and advocate @ Merck Sharp & Dohme (MSD)

11mo

"Finally, central planning and price regulation don’t lead to innovation." Those of us who worked in Central and Eastern Europe in the early 1990s on economic transition can only shout in loud agreement. I was so shocked by what I saw, that it completely changed my research course later. But it's amazing what a few decades will blur.

Greg Warren

Partner and Consulting Actuary, Axene Health Partners

11mo

Thank you John. We’ve got to work better together across disciplines and across industries to better align stakeholder incentives and reduce our pharmacy eco-system’s complexity.

Stanley Warren

Passionate about the Business of Pharmacy | Currently focused on LTC and LTC @ Home

11mo

All price negotiation are at the expense of the patient, and the reimbursement of the clinician/medication. There is no negotiation with the clinicians providing the product and after services/care. Prices are high becase we continue to buy into the free market rhetoric. The reality is the current market is so insidiously vertically integrated that its far from a “free market.” If not for the amassed power some of the insurer models should have been disrupted by simply by technology alone as they are ancient and obsolete. PBMs are the biggest contributors to high prices, and the big 3 wholesalers are not far behind.

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