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Congrats to the Pentax team on this milestone. Cryoablation is a proven winner in the GI space. As next gen cryoablation technologies continue to emerge we are poised for a significant advance in GI cancer treatment. Start up companies focused in cryoablation are a great ground floor opportunity for investors looking to get into next generation cancer treatments. Want in the game, learn more at www.PhaseTx.com #cryotherapy #lungcancer #bronchoscopy #endoscopy #EUS #CPSIBiotech #PhaseTx #cryosurgery #cryoablation #makeadifferece #NIH #pancreaticcancer #SBA #venturecaptial #familyoffce #cryo #getoffthebench #SBIR #NCI #medtech #tech #innovation #startups #entrepreneurs #entrepreneurship #vc #money #business #cancertherapy #investing #pancreas #breastcancer #ablation #thermalablation #cancer

Opioid Free Anesthesia (OFA) YouTube milestone >5,000 views of my Medtronic sponsored webinar Opioid Free Anesthesia What, Why, How Honored by the growing interest in my work Friedberg’s Triad                  Measure the brain                  Preempt the pain                  Emetic drugs abstain Friedberg’s Triad is a pathway to opioid free anesthesia (OFA) & better outcomes https://lnkd.in/gVUNn8z3

Fast-Track Pathway Significantly Reduces Costs and Hospitalization Time for Hip and Knee Arthroplasties A study from a Milan research hospital found that a fast-track pathway for elective hip and knee arthroplasty significantly reduced hospital stays and medical costs. The study compared data from two periods and found a 19.9% reduction in knee replacement costs and a 17% decrease in hip replacement costs. Hospitalization days also saw significant drops, with 37.6% fewer days for knee replacements and 39.2% fewer days for hip replacements. The fast-track pathway can make surgeries more accessible and cost-effective, aligning with the shift towards value-based care. The success of this approach could lead to policy changes and wider adoption of fast-track protocols for elective surgeries. For more details please click the link! https://lnkd.in/dRrXCSTX #marketaccess #reimbursement #pricing #hta #heor #healtheconomics #medicaldevices #pharmaceutical

While varicose veins can be uncomfortable and unsightly, patients who suffer from them have several minimally invasive treatment choices today. One of the most recently developed options is the VenaSeal closure system from Medtronic, which was approved for use by the Food and Drug Administration in 2015. VenaSeal uses a medical adhesive to seal off and collapse the diseased vein, which reroutes blood flow through nearby healthy veins. This specially formulated vein glue (the same type of adhesive that's been used in medical procedures since the 1950s, as an alternative to sutures) stays soft even after sealing off the vein, so you won't be able to feel it. It has great success rates, with a high vein closure rate. In a recent clinical study, 94.6% of patients treated with VenaSeal still had closed veins five years after their treatment. Best of all, what makes VenaSeal stand out from other treatments is that no compression stocking is needed, so you can exercise without restriction immediately following the procedure. No anesthesia is needed, no incisions are needed, and the discomfort related to both the procedure itself as well as discomfort during the recovery are less than with the other procedures out there. Visit our website at https://lnkd.in/ea6_hZVi to learn more and see if VenaSeal treatment is right for you. The Vascular Care Group is a leading independent group of board-certified vascular surgeons with extensive experience treating vascular disease including arterial and venous disease, vascular malformations and anomalies, fibroids, and pelvic venous disease. We offer a comprehensive range of testing and advanced treatment options in our state-of-the-art office-based labs and nationally accredited vein centers across New England. 𝗪𝗢𝗥𝗟𝗗 𝗖𝗟𝗔𝗦𝗦 𝗩𝗔𝗦𝗖𝗨𝗟𝗔𝗥 𝗖𝗔𝗥𝗘 𝗜𝗡 𝗬𝗢𝗨𝗥 𝗖𝗢𝗠𝗠𝗨𝗡𝗜𝗧𝗬. 𝗖𝗢𝗠𝗙𝗢𝗥𝗧𝗔𝗕𝗟𝗘. 𝗖𝗢𝗡𝗩𝗘𝗡𝗜𝗘𝗡𝗧. 𝗖𝗢𝗠𝗣𝗥𝗘𝗛𝗘𝗡𝗦𝗜𝗩𝗘.

Understanding Lidocaine Hydrochloride: More Than Just a Local Anesthetic 💉 Today, I want to highlight Lidocaine Hydrochloride, a versatile drug with significant applications in both anesthesia and cardiology. 🔹 Mechanism of Action: It works by blocking sodium channels in nerve cells, preventing the initiation and conduction of nerve impulses. This results in temporary loss of sensation in the targeted area. 🔹 Primary Use: Lidocaine is widely known as a local anesthetic, essential for numbing tissues during minor surgical procedures. Its rapid and effective pain relief is invaluable in various settings, from dental procedures to minor surgeries. 🔹 Antiarrhythmic Agent: Lidocaine also plays a critical role in managing ventricular arrhythmias, especially in emergencies. By blocking sodium channels in cardiac cells, it stabilizes the heart’s membrane, reducing excitability and helping restore normal rhythm. This makes it a vital tool in treating life-threatening arrhythmias following a heart attack. 🔹 Other Uses: Beyond its primary roles, lidocaine is used in various formulations for pain management, including topical applications for post-herpetic neuralgia and injectables for infiltrative and regional anesthesia. It is also sometimes combined with other medications to enhance their effects or reduce procedural pain. Understanding the multifaceted roles of medications like lidocaine is crucial for optimal patient care. By recognizing its diverse applications, we can better manage patient outcomes and contribute to more effective healthcare. #pharmacology #pharmd #anesthesia #cardiology

This study compares the effects of administering different fluids before spinal anesthesia on the spread of sensory block. The study involved 150 patients divided into three groups receiving normal saline, Ringer, or hydroxyethyl starch. The study found that there were no significant differences in demographic characteristics between the groups. However, the maximum block was higher in the normal saline group compared to the Ringer group, and the time taken to reach maximum block was longer in the Ringer group. Normal saline also had a longer duration of sensory block compared to Ringer and hydroxyethyl starch. This suggests that the choice of preload fluids can impact the level, distribution, and duration of sensory block in spinal anesthesia. https://lnkd.in/eB69SRCi

Per-Oral Endoscopic Myotomy (POEM) Offers Critical Guidelines 🪡 read our summary 👉 https://lnkd.in/drVx4bwB by Yang D, Bechara R, Dunst CM and Konda VJA in Gastroenterology

🔎 Explore the key findings from a study conducted by Francesco A Rasulo's team in Italy on the use of the PPI (pupillary pain index) during opioid-sparing anesthesia (OSA). ➡ The PPI serves as an objective measure of analgesic level in anesthetised patients.  ➡ The AlgiScan and PPI may be used after a brief training period.  ➡ A constant rate infusion of dexmedetomidine, as an adjuvant during general anesthesia, may improve and stabilise analgesia.  ➡ The use of pupillary pain index is a way to reduce opioid administration and maintain adequate analgesia. This study demonstrates the feasibility and efficacy of an opioid-sparing anesthesia strategy with dexmedetomidine. By reducing opioid reliance, this approach may offer significant benefits in terms of postoperative pain management and mitigating opioid-related adverse effects. For further insights, read the full article:  https://lnkd.in/dFJm2cze #Analgesia #Dexmedetomidine #OpioidReduction #Nociception #AlgiScan #PPI #Pupillometry

🌍𝗘𝘅𝗽𝗮𝗻𝗱𝗶𝗻𝗴 𝗦𝗰𝗵𝗲𝗹𝗶𝗻 𝗖𝗮𝘁𝗵𝗲𝘁𝗲𝗿® 𝗿𝗲𝗮𝗰𝗵 𝗶𝗻 𝗘𝘂𝗿𝗼𝗽𝗲 𝗮𝗻𝗱 𝗦𝗼𝘂𝘁𝗵 𝗔𝗺𝗲𝗿𝗶𝗰𝗮 🌍 I am excited to discuss the expanding global impact of the Schelin Catheter®, a key innovation in urological care. This innovation enables sterile intraprostatic local anesthetic injection. This catheter reshapes how urological procedures are performed, making them safer, more efficient, and more convenient.  🔹 Innovative application: The Schelin Catheter® allows for precise delivery of Lidocaine, Mepivacain or long-acting local anesthetics eventually with Adrenaline directly into the prostate. This reduces bleeding, minimizes blood loss, enhances visibility, increases resection weights, reduces operation time, and improves outcomes for TURP and various surgical procedures.  🔹 Transformative change: Traditionally dependent on hospital settings with general or spinal anesthesia, these procedures can now be efficiently managed in an office setting by urologists themselves, significantly improving the patient experience.  🔹 Proven efficacy: Integrated with the CoreTherm® Concept, the Schelin Catheter® has been part of over 13,000 successful cases in Scandinavia since 2005, demonstrating its effectiveness and safety.  🔹 Versatile applications: Over the past two years, this catheter has been used for various procedures, including:  · Water vapor therapy (Rezum).  · Prostatic Urethral Lift (Urolift)  · Core Therm  · TURP  · Green laser procedures  · HoLEP  🔹 Future applications: Research is ongoing to expand its use in diagnosing and treating chronic pelvic pain, aiming to eliminate the need for general anesthesia in these scenarios.  For those interested in understanding more about how the Schelin Catheter® can be integrated into your practice, or to learn more about its applications, please contact me! 

🌟 PRAC Announces Key Safety Updates 🌟 🔍 New Safety Recommendations for GLP-1 Receptor Agonists 🔍 PRAC has issued new measures to minimize the risk of aspiration and pneumonia aspiration in patients undergoing surgery with general anaesthesia or deep sedation while on GLP-1 receptor agonists, used for treating type 2 diabetes and obesity. Patients should inform their doctors about their medication before surgery to ensure safety. 💡 Important Safety Information for Healthcare Professionals: Glatiramer Acetate 💡 An EU-wide review confirmed that glatiramer acetate, a treatment for relapsing multiple sclerosis, is associated with anaphylactic reactions. These reactions can occur even months to years after starting treatment. Healthcare professionals are urged to educate patients about the signs and symptoms and to seek emergency care if needed. Treatment must be discontinued if an anaphylactic reaction occurs. For more detailed information, refer to EMA’s news announcement:https://lnkd.in/eKPBbPFf #Pharmacovigilance #PRAC #EMA #SafetyCommittee #Leadership #PharmaNews #GLP1ReceptorAgonists #GlatiramerAcetate #HealthcareProfessionals #PatientSafety #PublicHealth