NanoString Technologies, Inc.’s Post

Recently, my colleague @Philip Ramsey gave a noteworthy talk on statistics in #CMC.   It’s a promising time to be a part of cell and gene therapies, but on the statistical side of #CMC one big problem comes up with some frequency: System Complexity. As Philip Ramsey and Patricia McNeill of Lundbeck note, some treatments can involve 10-20+ critical quality attributes, each influenced by numerous interconnected process parameters. So how should statistical methods handle complexity in these systems? 💬 Phil offers the following: "You have to experiment in ways that capture interactive behavior. It's all about prediction and how well your models can interpolate over the design region." At @Predictum Inc., we address these challenges with our #SVEM methodology, a machine learning approach that ensures accurate predictive modeling. Check out #SVEM in the recording above. We also have the full webinar on our site. It’s free. No email signup needed. You might be surprised how quickly #SVEM will make a difference. 📺 Watch the full webinar at predictum.com: https://bit.ly/4atDEOM #JMP #processdevelopment #processimprovement #drugdevelopment #pharmaceuticals

The methodology beneath this particular application is known as #SVEM, a machine learning method for small sets of data (as little as 20 or 30 observations). In this post (https://lnkd.in/gx9i2Acm) it's talked about in terms of CMC/pharmaceuticals. But the same methodology has been applied in other areas from asphalt to advanced chemical formulations. It's a game changer and I encourage you to look into it (https://lnkd.in/gpcFccJt).

Learn about the flexible side of #singlecell in this blog, covering FAQs about sample prep for Chromium Single Cell Gene Expression Flex. Should I start with fresh, frozen, or fixed samples? How can I profile #FFPE? Any best practices for storage and transport? QC considerations, stopping points? Read on to explore all of these questions and find out how to run single cell assays on your schedule.

Ever wish you could clone yourself to get more done? 🤔 Just think of the time you would save! ⏩ Back in the lab, let us help get your gene synthesis clones faster with recently reduced production times. ⏱️ GeneArt cloned genes for complex and non-complex sequences delivered reliably and with a flexible, custom process that allows you to get the exact sequence you need. Start designing: https://lnkd.in/gYgQFxWw #geneart #clonedgenes #genesynthesis

Ever wish you could clone yourself to get more done? 🤔 Just think of the time you would save! ⏩ Back in the lab, let us help get your gene synthesis clones faster with recently reduced production times. ⏱️ GeneArt cloned genes for complex and non-complex sequences delivered reliably and with a flexible, custom process that allows you to get the exact sequence you need. Start designing: https://lnkd.in/gYgQFxWw #geneart #clonedgenes #genesynthesis

Ever wish you could clone yourself to get more done? 🤔 Just think of the time you would save! ⏩ Back in the lab, let us help get your gene synthesis clones faster with recently reduced production times. ⏱️ GeneArt cloned genes for complex and non-complex sequences delivered reliably and with a flexible, custom process that allows you to get the exact sequence you need. Start designing: https://lnkd.in/gYgQFxWw #geneart #clonedgenes #genesynthesis

Ever wish you could clone yourself to get more done? 🤔 Just think of the time you would save! ⏩ Back in the lab, let us help get your gene synthesis clones faster with recently reduced production times. ⏱️ GeneArt cloned genes for complex and non-complex sequences delivered reliably and with a flexible, custom process that allows you to get the exact sequence you need. Start designing: https://lnkd.in/gYgQFxWw #geneart #clonedgenes #genesynthesis

#Need a Microplate Reader this year? 🤔 Listen to our webinar #"Critical Considerations for Choosing the Right Microplate Reader" Choosing the best Microplate readers for your lab can be confusing. 😕 They are essential instruments for a vast range of applications, from basic ELISAs and DNA quantification to complex gene expression and enzyme kinetic assays. With so many options and functionalities available, it can be difficult to choose the optimal reader for your need.   In this webinar:   #Learn what features to look for when choosing a microplate reader #Explore example applications and case studies #Discover the benefits of combining microplate readers with automated imaging systems to improve lab efficiency and get results faster.    Webinar recording:  <https://lnkd.in/ejQ_mgtt>   For more #information, please contact us: infoboxeu@moldev.com  

Choosing the Right Microplate Reader

Ever wish you could clone yourself to get more done? 🤔 Just think of the time you would save! ⏩ Back in the lab, let us help get your gene synthesis clones faster with recently reduced production times. ⏱️ GeneArt cloned genes for complex and non-complex sequences delivered reliably and with a flexible, custom process that allows you to get the exact sequence you need. Start designing: https://lnkd.in/gYgQFxWw #geneart #clonedgenes #genesynthesis