Our human body is made of 30+ trillion cells that as we age, become less and less healthy due to wear and tear, poor lifestyle choices, overflowing our proverbial rain barrel with toxins, inflammation and oxidative stress. This CELLULAR AGING starts gradually and depends on the above factors, as well as genetics. Typically our cells and mitochondria are efficient and resilient in early adulthood, but sometimes in our mid 30ies and 40ies, the biogenesis of mitochondria decreases and our cells start producing less and less energy. This is the time oxidative damage and mutations in mitochondrial DNA (mtDNA) begin to accumulate. By the time we hit your 60, low energy, fatigue, slow metabolism and reduced tissue repair have been a result of significant declines in mitochondrial function our body has gone through especially in your 50ies and depending on the above factors, our mitochondria and cells will have aged more or less. To max out your cellular health, it is adamant to eat healthy, exercise, sleep deep as well as practice intermittent fasting. Totake it up to the next level and optimize, you support your cellular health with supplements such as Nicotinamide Riboside. (NR) is a form of vitamin B3 (niacin) and is a precursor to nicotinamide adenine dinucleotide (NAD+), a molecule critical for energy metabolism and cellular function. NR has gained attention for its potential role in promoting healthy aging, improving mitochondrial function, and supporting cellular repair mechanisms in the health, wellness and longevity realm amongst anyone interested in: 1. Boosting NAD+ Levels and support energy metabolism and cell repair. 2. Promoting Healthy Aging by slowing down age-related decline in cellular function and enhancing mitochondrial health and improving tissue repair. 3. Improving Energy Metabolism as NAD+ is crucial for converting food into cellular energy (ATP).NR can support this process. 4. Supporting Brain Health as NR may improve cognitive function by enhancing neuronal energy supply and repair mechanisms. It has potential neuroprotective effects, which could lower the risk of age-related conditions like Alzheimer’s. 5. Enhancing Heart Health by supporting mitochondrial health in heart cells and reducing nflammation and oxidative stress, which are linked to heart disease. 6. Muscle Recovery and Endurance by optimizing energy metabolism. 7. DNA Repair and Cellular Stress as NAD+ is essential for activating enzymes like PARPs, which are involved in DNA repair and protecting against oxidative damage. If you you like help selecting this supplement from our professional Fullscript account where you get quality third party certified supplements, free shipping on orders $50+ and a discount, Sign up here: https://lnkd.in/gAzqb_-e #healthyaging #healthandwellness #mitochondrialhealth #healthoptimization #nicotimideriboside
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As a 46 year old, I am adding this supplement to my personal HEALTH & WELLNESS TOOLBOX 🧰 in 2025 to BOOST MY ENERGY, PRODUCTIVITY & to help me live to my FULLEST HEALTH SPAN POTENTIAL. Here is why you may want to consider adding NR to yours: #healthandwellness #healthyaging #cellularhealth #healthoptimization P.S. I have been into health, wellness, and fitness my entire life. I believe in an integrative approach to medicine via lifestyle first, mindful supplementation and then pharmacological interventions.
Our human body is made of 30+ trillion cells that as we age, become less and less healthy due to wear and tear, poor lifestyle choices, overflowing our proverbial rain barrel with toxins, inflammation and oxidative stress. This CELLULAR AGING starts gradually and depends on the above factors, as well as genetics. Typically our cells and mitochondria are efficient and resilient in early adulthood, but sometimes in our mid 30ies and 40ies, the biogenesis of mitochondria decreases and our cells start producing less and less energy. This is the time oxidative damage and mutations in mitochondrial DNA (mtDNA) begin to accumulate. By the time we hit your 60, low energy, fatigue, slow metabolism and reduced tissue repair have been a result of significant declines in mitochondrial function our body has gone through especially in your 50ies and depending on the above factors, our mitochondria and cells will have aged more or less. To max out your cellular health, it is adamant to eat healthy, exercise, sleep deep as well as practice intermittent fasting. Totake it up to the next level and optimize, you support your cellular health with supplements such as Nicotinamide Riboside. (NR) is a form of vitamin B3 (niacin) and is a precursor to nicotinamide adenine dinucleotide (NAD+), a molecule critical for energy metabolism and cellular function. NR has gained attention for its potential role in promoting healthy aging, improving mitochondrial function, and supporting cellular repair mechanisms in the health, wellness and longevity realm amongst anyone interested in: 1. Boosting NAD+ Levels and support energy metabolism and cell repair. 2. Promoting Healthy Aging by slowing down age-related decline in cellular function and enhancing mitochondrial health and improving tissue repair. 3. Improving Energy Metabolism as NAD+ is crucial for converting food into cellular energy (ATP).NR can support this process. 4. Supporting Brain Health as NR may improve cognitive function by enhancing neuronal energy supply and repair mechanisms. It has potential neuroprotective effects, which could lower the risk of age-related conditions like Alzheimer’s. 5. Enhancing Heart Health by supporting mitochondrial health in heart cells and reducing nflammation and oxidative stress, which are linked to heart disease. 6. Muscle Recovery and Endurance by optimizing energy metabolism. 7. DNA Repair and Cellular Stress as NAD+ is essential for activating enzymes like PARPs, which are involved in DNA repair and protecting against oxidative damage. If you you like help selecting this supplement from our professional Fullscript account where you get quality third party certified supplements, free shipping on orders $50+ and a discount, Sign up here: https://lnkd.in/gAzqb_-e #healthyaging #healthandwellness #mitochondrialhealth #healthoptimization #nicotimideriboside
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Boost Your Brain Health with the Mediterranean Diet! Did you know that what we eat can have a profound impact on our brain health as we age? Recent research has shown that following a Mediterranean diet can be a game-changer when it comes to protecting our brains against cognitive decline, particularly in relation to Alzheimer's disease. The Mediterranean diet is a way of eating that emphasizes fruits, vegetables, whole grains, legumes, nuts, and healthy fats, while limiting red meat and processed foods. It draws inspiration from the traditional eating patterns of countries bordering the Mediterranean Sea, such as Greece, Italy, and Spain. A growing body of scientific evidence has revealed the fascinating connection between the Mediterranean diet and its potential to reduce the risk of Alzheimer's disease. Studies have shown that individuals who closely adhere to this eating plan exhibit lower levels of Alzheimer's biomarkers in their blood. Furthermore, researchers have found that the Mediterranean diet may play a crucial role in preserving brain volume and reducing brain atrophy in old age. This means that following this dietary pattern could help protect the structure and function of our most vital organ, the brain, as we grow older. Why is the Mediterranean diet so effective in promoting brain health? It's likely because this way of eating is rich in antioxidants, healthy fats, and nutrients that are essential for brain function. These components help reduce inflammation, support the growth of new brain cells, and improve the overall health of our blood vessels. So, if you're interested in safeguarding your brain health as you age, why not give the Mediterranean diet a try? Remember, eating in a way that nurtures both our bodies and minds is not only a delicious and enjoyable experience but also a powerful tool for preventing cognitive decline and promoting a healthy, vibrant life. Like and share this post if you believe in the power of the Mediterranean diet for brain health! Let's spread the word and help others on their journey to optimal brain health! Keep reading! https://lnkd.in/gTUHVdwE #DHPSP2024 #MediterraneanDiet #AlzheimerPrevention #BrainHealth #HealthyLiving #MindfulEating #StaySharp #StayHealthy
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🧣 Thyroid Function: Small Gland, Big Impact 🎀 Thyroid hormones are vital for maintaining overall health and well-being. These hormones regulate metabolism, energy production, growth, and development, playing a critical role in the body's basal metabolic rate, ensuring efficient calorie burning, and sustaining vitality. Proper levels of thyroid hormones are crucial for brain development, organ function, cardiovascular health, and cognitive processes. Imbalances in thyroid hormone levels can lead to significant health issues, underscoring the importance of regular thyroid function testing. The global thyroid function testing market is experiencing significant growth, projected to reach approximately USD 8.9 billion by 2033, with a CAGR of 6.33% from 2024 to 2033. This growth is driven by advancements in diagnostic technologies and increasing awareness about thyroid disorders. BSK BASIC's Comprehensive Thyroid Function Test Kits BSK BASIC offers a range of rapid test kits for thyroid function, providing reliable and rapid results essential for diagnosing and managing thyroid health. These test kits include: 🏅 T3 (Triiodothyronine) Test o Linearity Range: 0.6-10 nmol/L 🏅 T4 (Thyroxine) Test o Linearity Range: 10-320 nmol/L 🏅 FT3 (Free Triiodothyronine) Test o Linearity Range: 1-50 pmol/L 🏅 FT4 (Free Thyroxine) Test o Linearity Range: 2-70 pmol/L 🏅 TSH (Thyroid Stimulating Hormone) Test o Linearity Range: 0.1-100 mlU/L These test kits are designed to provide accurate, quick, and reliable results, making them invaluable tools for healthcare professionals in diagnosing and managing thyroid disorders.BSK BASIC's FIA Immunoassay rapid test kits for thyroid function are crafted to meet the growing demand for precise and swift diagnostic solutions. By offering a comprehensive range of tests with rapid reaction times and accurate results, BSK BASIC supports healthcare professionals in effectively diagnosing and managing thyroid health. As the global market for thyroid function testing continues to expand, BSK BASIC remains at the forefront, providing innovative solutions to enhance thyroid health and overall wellness. #ThyroidFunction #Triiodothyronine #Thyroxine #FreeTriiodothyronine #FreeThyroxine #ThyroidStimulatingHormone #FIAImmunoassayAnalyzer #QuantitativeTest #FSH #T3 #T4 #FT3 #FT4
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🌟 Understanding the Thyroid Gland: Anatomy and Function 🌟 The thyroid gland, a small butterfly-shaped organ located at the base of the neck, plays a crucial role in our overall health and well-being. Despite its size, this gland has a significant impact on our metabolism, growth, and development. Here’s a closer look at its anatomy and functions: 🔍 Anatomy of the Thyroid Gland: Location: The thyroid gland is situated in front of the trachea and just below the larynx. It consists of two lobes (right and left) connected by a narrow isthmus. Structure: The thyroid is made up of follicles, which are spherical sacs filled with a colloid substance containing thyroglobulin. The walls of these follicles are lined with follicular cells that produce thyroid hormones. Hormone Production: The gland synthesizes two primary hormones: Thyroxine (T4): Contains four iodine atoms and is the main hormone secreted by the thyroid. Triiodothyronine (T3): Contains three iodine atoms and is the more active form of thyroid hormone, primarily converted from T4 in peripheral tissues. 🛠️ Functions of the Thyroid Gland: Metabolism Regulation: The thyroid hormones (T3 and T4) play a pivotal role in regulating the body’s metabolism. They influence how our body uses energy, impacting everything from weight management to temperature regulation. Growth and Development: These hormones are essential for normal growth and development, particularly during infancy and childhood. They are critical for brain development and skeletal growth. Heart and Digestive Health: The thyroid hormones help regulate heart rate and maintain healthy cholesterol levels. They also support proper digestion and nutrient absorption. Calcium Regulation: The thyroid gland produces calcitonin, a hormone that helps regulate calcium levels in the blood and supports bone health. 💡 Why Thyroid Health Matters: An imbalance in thyroid hormone levels can lead to various health issues, such as hypothyroidism (underactive thyroid) and hyperthyroidism (overactive thyroid). These conditions can significantly impact energy levels, mood, weight, and overall health. Regular check-ups and monitoring of thyroid function are essential for maintaining optimal health. 🩺 As a healthcare professional, I encourage everyone to stay informed about their thyroid health and consult with a specialist if any symptoms arise. 🔗 Let's keep the conversation going! Share your thoughts on thyroid health or experiences in the comments below! #ThyroidHealth #Endocrinology #Wellness #HealthcareEducation #Metabolism #Growth #HealthMatters
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Do you want to keep your brain sharp and healthy, while also preventing neurological diseases such as Alzheimer's down the road? At the center of events leading to brain disease is a disrupted gut community. As previously stated, In 2013, the US spent $50,000 annually caring for each dementia patient in this country, amounting to $200 billion annually (roughly 4 million patients nationwide). It is becoming increasingly undeniable to not correlate the growing number of people experiencing brain disorders and disease, and the changes we have made in our diets over the past generation. What is linked to dementia? High blood sugar strongly links to dementia, even slightly high blood sugar levels that are well below the diabetes threshold (based on a 2,000-person study by the University of Washington with an average age of 76 years). How do you keep your brain strong and healthy then? According to the Journal of Neurology, Neurosurgery, and Psychiatry in 2013, elderly people who added more fat (olive oil, nuts, avocado, eggs, etc…) to their diets maintained cognitive abilities much better over 6 years than those who ate low fat According to Dr. James M. Hill at Louisiana State University – Good gut bacteria is capable of producing important brain chemicals like BDNF, gamma-aminobutyric acid (GABA), and glutamate. BDNF is involved in neurogenesis and also is responsible for protecting existing neurons. GABA is also a neurotransmitter in the central nervous system. All in all, if you take care of your microbiome by eating and drinking products that contain probiotics and healthy bacteria and eat lots of healthy fats, your brain will have a long, healthy life. Article: https://lnkd.in/g4bKqagY Sources: 1) Dicks L. M. T. (2022). Gut Bacteria and Neurotransmitters. Microorganisms, 10(9), 1838. https://lnkd.in/gDYdBNur 2) Klimova, B., Novotny, M., Schlegel, P., & Valis, M. (2021). The Effect of Mediterranean Diet on Cognitive Functions in the Elderly Population. Nutrients, 13(6), 2067. https://lnkd.in/g_WfYGeX 3) Perlmutter, D. (2017). Brain maker: The power of gut microbes to heal and protect your brain - for life. Yellow Kite.
Prevent your Brain from Deteriorating — Scoby Drinks
scobydrinks.com
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In this study by Gabriel S.S. Tofani et al., the authors report how the gut microbiota regulates stress responsivity via the circadian system in mice. The stress and circadian systems are governed by complex biological processes. On one side, the hypothalamic-pituitary-adrenal (HPA) axis modulates stress via the production of glucocorticoid hormones, such as cortisol and corticosterone. On the other, the circadian rhythm is regulated by the autonomic nervous system, involving the suprachiasmatic nucleus (SCN) and the paraventricular nucleus (PVN) of the hypothalamus. It is known that glucocorticoids display a peak at the sleep/wake transition, functioning as one of the main synchronizing circadian cues from the brain to the periphery. The major contribution of this study is to explain how the gut microbiome modulates stress and the circadian system in an integrated way during the daily cycle. To work on this complex hypothesis, they compared control mice with a healthy microbiome to antibiotic-treated and/or germ-free mice with a disrupted microbiome at different times of the day. They first confirmed that the gut microbiome oscillates throughout the day, with significant variations, especially for strains of the genus Lactobacillus, specifically belonging to the species L. reuteri and L. jensenii. These variations affected corticosterone modulation by the HPA axis in a time-dependent manner. When they disrupted the gut microbiome, the analysis of gene expression (RNA-Seq) in the SCN, hippocampus, and amygdala showed that genes modulating circadian rhythms and stress were also disrupted. Integrated analysis of the transcriptome and the metabolome in the same brain regions also identified rhythmic changes induced by the microbiome status, including changes in glutamate metabolism in both the hippocampus and amygdala, with glutamate being the major excitatory neurotransmitter. They then assessed that microbial depletion disrupted the rhythmic patterns of the HPA axis. Analysis of gene expression showed major changes in gene networks in the hypothalamus and the pituitary gland, but not in the adrenal gland, implying that microbiome disruption mainly affects the brain. In addition, the hypothalamic blood-brain barrier was impaired in microbially depleted animals, as shown by the arrhythmic expression of tight junction proteins of that barrier and the consequent functional alteration. Finally, they showed that disruption of the microbiota dysregulated the peak of corticosterone and that diurnal oscillations of gut microbes led to changes in corticosterone release. Further studies will test whether microbiome-based therapeutic interventions may modulate these critical pathways connecting the gut and the brain. Open access Cell Metabolism https://lnkd.in/eNc85wmA See also resume in Neuroscience News https://lnkd.in/eaWfcGzs #gutbrainaxis #stress #circadianrythms
Gut microbiota regulates stress responsivity via the circadian system
sciencedirect.com
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🧠 Whey Protein for Brain Health? Here's What the Latest Study Found I just discovered a fascinating study that could change our thoughts about nutrition and brain health. Researchers tested whether whey protein powder, packed with milk fat globule membrane (MFGM), taurine, and B vitamins, could improve cognitive function in older adults with mild cognitive impairment (MCI). Over 12 months, they tracked 107 participants, comparing those taking 15g of whey protein daily to a placebo group. The results were impressive! 🥼 The group taking whey protein improved their global cognitive scores significantly more than the placebo group—by 1.81 points on the MoCA test (a key measure of cognitive function). They also saw gains in other cognitive tasks like the DSST test, and there were very few side effects reported. This adds to the growing evidence that targeted nutrition can play a big role in supporting brain health, especially as we age. If you're as intrigued as I am, this might be one to keep an eye on! 🚀 💡 Is Improving Muscle the Secret to Brain Health? This study got me thinking—both whey protein and creatine are known for their muscle-boosting effects, but they also show benefits for brain health. Creatine, in particular, has been linked to memory improvements in various studies. Now, with evidence that whey protein improves cognitive function in older adults, could there be a deeper connection? One hypothesis might be that improving muscle health enhances overall metabolic and vascular health, which indirectly supports brain function. Another possibility is that these supplements influence pathways like insulin signaling or inflammation, which affect both muscle and brain health. It’s intriguing to think that optimizing muscle health could be a gateway to protecting cognitive function as we age. What do you think—is the “muscle-brain connection” an overlooked key to aging well? 🤔💪🧠 https://lnkd.in/gE2Y5-Yw #whey #creatine #fitness #brainhealth #MCI #neuroscience
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We have known about oxidative stress for decades—a silent elephant in the room that we chose to ignore. Its ramifications extend beyond scientific discovery to societal and financial implications. First recognized as a factor in cellular damage in the mid-20th century, oxidative stress has since been linked to devastating diseases like Alzheimer’s, Parkinson’s, cancer, and cardiovascular disorders. Yet, early intervention was largely overlooked, often because it required a shift from short-term fixes to long-term prevention and holistic approaches. As a result, the cost of inaction is now undeniable. Oxidative stress impacts everyone—your grandmother, father, sister, brother, and even those in high places, such as senators and policymakers. It is only when these conditions affect people with influence that urgency resurfaces. Imagine how many lives could have been spared had we acted earlier—intervening with antioxidants, lifestyle changes, or treatments targeting oxidative pathways. The role of oxidative stress in diseases like Alzheimer’s and Parkinson’s is clear. Oxidative damage leads to the degeneration of neural circuits, impairing memory, movement, and cognition. This damage accumulates over time, leaving many with advanced diseases before symptoms appear. Failing to prioritize prevention has allowed this process to ravage millions, limiting opportunities to develop innovative treatments. Pharmaceutical companies have explored numerous compounds targeting oxidative stress, yet many promising drugs were abandoned. Tirilazad Mesylate, a lipid peroxidation inhibitor, was discontinued after clinical trials showed insufficient efficacy. Similarly, NXY-059, a neuroprotectant for stroke, failed in late-stage trials. Liposomal Nrf2 activators, though promising, struggled with formulation and clinical translation. These failures, however, do not signify a dead end. Rather, they highlight the need for innovation—developing compounds that mimic powerful antioxidants while addressing research complexities. This problem is vast, requiring precision in identifying pathways and parameters. The elephant in the room—the escalating burden of oxidative stress—demands action. We must redirect focus toward prevention and treatments that address oxidative stress at its root. By investing in research on bioenergetics, inflammation pathways, and neuroplasticity, and by leveraging tools like transcranial magnetic stimulation, antioxidants, and lifestyle interventions, we can turn this challenge into an opportunity. The question is, will we continue to let the elephant grow, or will we confront it? The failure to act now will only deepen the consequences for future generations. Addressing oxidative stress isn’t just about science—it’s about prioritizing human health and well-being for all. The time to act is now. Lives depend on it.
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Fasting, or voluntary abstention from meals for a specified amount of time, has received a lot of attention in recent years because of its possible scientific benefits. Many studies indicate that fasting has a good effect on many elements of health, including longevity and cellular repair as well as metabolic health. But it's important to proceed cautiously when fasting, considering each person's unique health situation and consulting medical professionals for advice. Health of the Metabolic Process: Fasting has several advantages, one of which is that it can improve metabolic health. Studies show that fasting can increase blood sugar regulation, insulin sensitivity, and fat burning. Those who suffer from diseases like diabetes and obesity may have to deal with significant impacts from these complications. Fasting has the potential to improve the management and preventive effects of metabolic disorders by influencing important metabolic indicators. Cellular Repair and Autophagy: Fasting triggers a fascinating process called autophagy, wherein cells remove damaged components and recycle them. This cellular "spring cleaning" promotes overall cellular health and longevity. Autophagy is crucial for the body's ability to repair and rejuvenate, and fasting seems to stimulate this process, potentially contributing to a healthier cellular environment. Brain Function: The impact of fasting on brain health is another area of growing interest. Studies suggest that fasting may stimulate the production of brain-derived neurotrophic factor (BDNF). BDNF is a protein that supports the growth and maintenance of neurons, playing a crucial role in cognitive function. By promoting the production of BDNF, fasting may have neuroprotective effects, potentially lowering the risk of neurodegenerative disorders and enhancing overall brain function. Heart Health: Fasting has been linked to improvements in various cardiovascular risk factors. Research indicates that fasting can lead to reduced inflammation, blood pressure, and cholesterol levels. These effects collectively contribute to better heart health and a decreased risk of cardiovascular diseases. Incorporating fasting into a lifestyle may serve as a proactive measure for maintaining cardiovascular well-being. Longevity and Ageing: Some studies suggest that fasting could influence cellular processes associated with ageing, potentially extending lifespan. By modulating factors such as oxidative stress and inflammation, fasting may contribute to a slowing of age-related processes. Stay Healthy 💚 📌Unshared knowledge will vanish! 🎗 Share, like, and comment for others to see. Thank you for your support! 👉Follow me and 👉 Activate Bell 🛎️ for all posts as well as additional technical and educational content!💪🏆 #innovation #creativity #technology #letsconnect #future #education #knowledge #topvoice #amazing #prosthetics #medtech #healthtech #Wellness #medical #human #body #fasting #sustainability
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Check out Dr. Matt Chalmers's article today. Dr Chalmers Path to Pro - TUDCA The importance of TUDCA (Tauroursodeoxycholic acid) in maintaining overall health, particularly focusing on its benefits for brain health and neurodegenerative diseases. The interconnectedness of bodily systems, highlighting the crucial role of the liver and lymphatics in brain function. The significance of proper nutrition, especially during fasting, to ensure adequate nutrient intake and avoid detrimental effects such as muscle loss. The need for essential nutrients like Coenzyme Q10, methylated B vitamins, and omega-3 fatty acids, particularly for optimal brain function. Additionally, Encourages viewers to research TUDCA and its potential benefits, especially for those concerned about neurodegenerative diseases like dementia and Alzheimer's. Follow his Substack for more: https://lnkd.in/geEBX-eP Follow Matt Chalmers Linked Click the link to read the entire article: https://lnkd.in/gz7xvqAw #BrainHealth #TUDCA #Nutrition #Fasting #HealthTips #Wellness #Neurology #LiverFunction #OptimalHealth #BrainFunction #CoenzymeQ10 #Omega3 #MethylatedB12 #HealthyLiving #HolisticHealth
Dr Chalmers Path to Pro - TUDCA
drchalmers.substack.com
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