What’s the secret to achieving a 10-fold increase in GLP-1 agonist bioavailability in our LXM.2 oral solid tablet? The addition of a permeation enhancer (PE) to the formulation improves active pharmaceutical ingredient (API) absorption by reducing tight junctions in the duodenum, enabling the API to pass through the intestinal barrier into the bloodstream. However, PEs are known for local and gastrointestinal irritation. We lowered the total dose of PE by utilizing our novel Multi-compartment Microtablet design. Learn more about our innovative products enabled by our powerful manufacturing capabilities in our webinar with CEO Helmut Kerschbaumer: https://lnkd.in/eW2VCJ3m #DrugDevelopment #GLP1 #Agonist #Obesity #InnovateWithUs #SmartDrugDelivery #LXM2 #PermeationEnhancer #SPIDTechnology #LaxxonMedical
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Check out AVT Pharma's high-quality Egg Phosphatidylglycerol (for injection) EPG, a key ingredient in alprostadil and a vital auxiliary emulsifier. Learn more about this phospholipid found in lung surfactants and its role in fetal lung maturity at: https://lnkd.in/gWNam5Hm #pharmaceuticals #healthcare #lunghealth #AVTPharma
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🚨 An important update for pharmaceutical manufacturers: A guidance document has recently been released regarding nitrosamine impurities in medications. Even in trace amounts, nitrosamines pose serious health risks to patients as they are carcinogenic compounds. Here's the good news: by closely monitoring the concentration of nitrites in pharmaceutical products and raw materials, we can prevent nitrosamines from forming Our latest Application Note outlines how we analyze nitrite in duloxetine hydrochloride using ion chromatography (IC) with direct UV/VIS detection. Explore now https://brnw.ch/21wJBTe 💊 #PharmaceuticalSafety #NitrosamineControl #PharmaIndustry #MetrohmIndia #Metrohm #IonChromatography #IC #Nitrosamine
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S Mixon S Mixon pharmaceutical grade copper peptides. Skin care that works because we use ingredients that you just can’t get from over-the-counter products. Join us for learning and fun. The results speak for themselves. #copperpeptides #peptideskimcare #peptideserum #fyp #learnontiktok #pharmacistsoftiktok #skincarepharmacist #olderskin #olderskinrenewed #beautyover60 #agingwell #antiagingbundle #antiaging #maturebeautyover50 #skincareover50
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Did you know? Oil-based tinctures are poorly absorbed across the oral mucosa if at all. Patients’ sense of rapid onset are likely explained by Classical Conditioning. Pharmaceutical oral-mucosal sprays like Sativex and Epidiolex use surfactants and alcohols to improve bioavailability across normally impervious membranes. #ACS #Cannabis #Cannaspecialists #Sativex #Peidiolex
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Are you aware of the many factors that shape the gut microbiota and what defines a "healthy" gut microbiota? By taking this free CPD module you will learn the factors that have an impact and gain a toolkit for when advising patients on supporting their gut health with the use of probiotics, plus you can use it towards your revalidation with the General Pharmaceutical Council. https://lnkd.in/gepNvFvg
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💡 Compendial test for sterility The compendial test for sterility is based on membrane filtration or direct inoculation. The 14-days incubation period enables the reliable detection of stressed and slow-growing microorganisms, but also defines the earliest possible release time. Over the last 30 years, Labor LS has built up a wealth of experience of more than 3,500 product and customer-specific method suitability tests including highly effective antimicrobial active pharmaceutical ingredients and challenging product matrices. ▶ Please contact our experts if you have any questions and get your free access to the original publication "Praxisnahe Implementierung eines schnellen Sterilitätstests mittels Real-Time PCR" published in PharmInd. https://lnkd.in/ePs_EPQm #sterilitytest #sterilitytesting #sterility
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Sniffles dramatically "Spring is beautiful they said...” 🤧🐝🌸🌳 Are you one of many that suffer from pesky hay fever? Constantly stocked up on antihistamines? Well, us too. In June's Map of the Month, we use Raman to examine a widely used antihistamine formulation that contains the active pharmaceutical ingredient (API) cetirizine hydrochloride (CTZ). Find out how the RM5 can detect the API and other important compounds, and visualise their distribution within a drug formulation in our latest Map of the Month. https://ow.ly/OwAN50S8628 #MyEdinburghInstrument #pharmaceutical
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Cholesterol is used in topical pharmaceutical preparation as____? a)Emulsifying agent b)Emollient c)Improve water absorbing power of ointments d)All of above Read answer in following https://lnkd.in/dia5YgMu
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Cholesterol is used in topical pharmaceutical preparation as____? a)Emulsifying agent b)Emollient c)Improve water absorbing power of ointments d)All of above Read answer in following https://lnkd.in/dia5YgMu
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The carrier fraction of coarse particles is used to facilitate the pharmaceutical filling and metering process of formulations for dry powder inhalers. However, it provides no benefit to the patient - it impacts in their mouth and throat during inhalation, and any drug particles still attached do not reach the lung, and can lead to unwanted side effects, and cause coughing. The left image shows the formulation as filled into the Quattrii blister, comprised of blue "mimic" drug and coarse lactose carrier particles. The right image shows what is retained within the Quattrii blister following inhalation. What makes Quattrii unique is its ability to retain the majority of the carrier fraction in the blister while efficiently delivering a fine aerosol of drug to the lungs. We’re excited to share more about Quattrii at Drug Delivery to the Lungs Conference (DDL) next week, and look forward to seeing you there! #DDL2024 #inhalation #respiratory
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