Heba Ismail’s Post

96 WELL PLATES FOR DIFFERENT APPLICATIONS • Cell Culture • Immunology (ELISA) • High-Throughput Screening Microplates • Storage Microplates • Sapphire PCR Microplates #AnalitikKimya #greinerbioone

We are breaking new ground in immunology and inflammation, targeting the previously undruggable VAV1 protein, a key regulator of T- and B-cell receptor activity. Sharon Townson, Chief Scientific Officer, and Marisa P., Director of Target and Discovery Biology, discuss MRT-6160 - Monte Rosa’s potent, highly selective, and orally bioavailable, investigational VAV1-targeted molecular glue degrader - and its potential in diseases like IBD and rheumatoid arthritis. Watch the full video: https://bit.ly/4eBqjXi #immunology #inflammation #biotech

ELISpot immunoassays are essential tools for detecting and quantifying cytokine-secreting cells at the single-cell level. Confidently detect Human IL-6, IFN-γ, and TNF-α and drive your immunology research further. https://bit.ly/4cmZqoH

Here is a quick B-cell and antibody cheat sheet for people who may not feel all that familiar with immunology. Did you know the "B" in B-cell is named after the Bursa of Fabricus? It's an organ in chickens where they were first discovered (it's also where they are derived from in birds). Mammalian B-cells (human ones included) originate from the bone marrow.

ELISpot immunoassays are essential tools for detecting and quantifying cytokine-secreting cells at the single-cell level. Confidently detect Human IL-6, IFN-γ, and TNF-α and drive your immunology research further.

Baltic-Polish School of Immunology (BPSI2025) that will take place in Vilnius on May 12-13, 2025. Organized together with Baltic and Polish Immunological Societies and kindly supported by the European Federation of Immunological Societies (EFIS)/European Journal of Immunology (EJI), this event aims to promote regional collaboration of immunologists with a particular focus to a dialogue between researchers and medical doctors, between young and experienced immunologists. The regional Schools of Immunology are expected to become traditional events organized every year in a different neighboring country. The trend started in 2023 with the ABC7 Summer School in Tallinn (Estonia) followed by the School of Immunology “50 Shades of Immunology” in 2024 in Bialystok (Poland). The scientific program of BPSI-2025 will cover 4 broad thematic areas: Host-pathogen interaction, Tumor immunology, Sterile inflammation and autoimmunity, Inborn errors of immunity.

🔬 How can humanized nanobodies improve therapeutic precision? A recent study by Charlotte Deane in Frontiers in Immunology highlights how nanobody humanization reduces immunogenicity while retaining high specificity. These advancements will make nanobodies pivotal tools in precision medicine. Key benefits of humanized nanobodies: • Reduced immune response risk: Safer for therapeutic use in humans. • High antigen specificity: Maintains precise targeting capabilities. • Broad applications: Humanized nanobodies are reshaping healthcare from oncology to diagnostics. 🔍 Why this matters: Humanized nanobodies are bridging the gap between innovation and practicality, offering safer, more effective therapeutic solutions. 📖 Read the full paper here: https://lnkd.in/gkiUHA-f #NanobodyInnovation #HumanizedNanobodies #PrecisionTherapeutics #Immunology

🌐 T-FINDER: Revolutionizing TCR and Ligand Discovery in Immunology 🔬 A new method in immunology research! "T-FINDER: A highly sensitive, pan-HLA platform for functional T cell receptor and ligand discovery" was recently published in Science Advances 🟠 Rapid identification of T cell receptors (TCRs) & their ligands, crucial in various diseases. 🟢 Decodes both CD4 & CD8 TCRs, targeting human leukocyte antigen (HLA) haplotypes. 🔵 Integrates a sensitive TCR signaling reporter with an advanced antigen processing system. 🟣 Identifies unknown peptide:HLA ligands from vast antigen libraries. 🟡 Unbiased, high-throughput platform, suitable for class II & I HLA-presented T cell epitopes 📚 Full article: https://buff.ly/43I0IaM 📢 Join the Conversation 📢 Share your thoughts, methods, and tools in the comments 👇 💬 #TCRDiscovery #ScienceAdvances #HealthcareInnovation #Bioinformatics

Exploring Immunology: ELISA Practical Experience Today, I had the opportunity to dive deeper into the principles of immunology by performing an Enzyme-Linked Immunosorbent Assay (ELISA) in our lab session. This practical is a cornerstone in understanding how immunological techniques are applied in detecting and quantifying antigens or antibodies in various samples. What I learned: The significance of antigen-antibody interactions. How the enzymatic signal amplification enhances sensitivity. The critical role ELISA plays in diagnostics, research, and therapeutic monitoring. Hands-on experiences like this are invaluable for bridging theoretical knowledge with practical skills. Excited to explore more in the field of immunology! #Immunology #ELISA #Diagnostics #LabSkills #LearningByDoing

We’re leveraging our deep scientific expertise to revolutionize the treatment of immuno-inflammatory diseases by building an industry-leading pipeline of oral medicines. Today on the International Day of Immunology, hear from our VP of Clinical Development, Arsalan S. Qazi MD, PhD, on how we’re pioneering paradigm-changing medicines and the future of immunology. #DayofImmunology #TPD #ReinventingMedicine