Healome One’s Post

🫀 Help Us Improve Heart & Brain Health – Quick Survey! 🧠 We’re working on an Remote Ischemic Conditioning (RIC) device to help prevent and recover from ischemic cardiovascular and neurovascular diseases. And we need YOUR input! This survey, conducted by MBA students from #PekingUniversity and #UniversityCollegeLondon, aims to gather insights from European individuals on their thoughts and needs regarding this innovative device. Your feedback will directly help refine the RIC technology and support our research thesis. Survey Link: https://lnkd.in/gmibB5PS Privacy guaranteed – Your responses are anonymous and used for research purposes only. Thanks for being part of this project! #RICDevice #CardiovascularHealth #NeurovascularHealth #Stroke #EuropeanStrokeOrganisation #ESO #StrokeAllianceforEurope #SAFE #EuropeanStrokeOrganisationConference #ESOC #IschemicConditioning #HealthTech #Innovation #MedicalDevices #PreventiveMedicine #EuropeanSurvey #HealthResearch

🔍 Unveiling the Heart-Obesity Connection 🔍 Obesity and heart failure—two global health challenges intricately linked. But what bridges the gap between these conditions? Recent insights shed light on how various types of adipose tissue, particularly epicardial fat, play a role in heart failure development. Traditional obesity measures might miss the mark by ignoring fat location and molecular characteristics. Subcutaneous, visceral, and epicardial adipose tissues all have their story to tell, especially the latter, given its proximity to the heart. By diving into these depots, researchers are piecing together the puzzle of heart failure with preserved ejection fraction. This review in the Journal of the American College of Cardiology takes us deeper into understanding these mechanisms. As we expand our knowledge, we move closer to targeted interventions that could change countless lives. Healthier hearts ahead! 💓 Read Research 👉🏻 https://lnkd.in/da35v2A3 #research #pubmed

Short Story: As we are currently rolling out the new Cardiovascular Age (CVA) feature, if you are intrigued by it, please have a look at our white paper explaining the physiology behind it and our approach to estimate CVA and Pulse Wave Velocity (PWV) as well as our accuracy. Longer Story: This has been a unique opportunity for me to combine my physiological and technical knowledge to work on the concept of CVA. Some years ago, I discovered that aging is visible in our photoplethysmography (PPG) signal as changes in the shape of the pulse waveform. Back then I had the feeling that I was onto something. Over the last couple of years, our team has been laying the scientific foundation, developing the algorithm, and exploring the physiological factors behind these changes in PPG. We found that arterial stiffness, measured as carotid-femoral pulse wave velocity (cfPWV), has a strong correlation with age-related changes in PPG pulse shape, enabling us to estimate CVA and PWV. During this time, I've also had the chance to participate in a training school arranged by VascAgeNet COST action to learn more about vascular aging in general. Additionally, I had the opportunity to give an oral presentation on age-related changes in PPG at the Artery23 conference. In both events, I had encouraging discussions that helped strengthen my knowledge and vision. What I started was transformed into a reality together with several talented colleagues from science and other departments, resulting in a feature that I believe has a meaningful impact on monitoring and managing cardiovascular health ❤️ #CardiovascularAge #OuraRing #CardiovascularHealth #Innovation #Wearable

From the desk of Dr. Carolyn Hoffman ………………. Understanding Redox Signaling Molecules: The Guardians of Cellular Balance ⚖️ Redox signaling molecules might sound complex, but they play a simple and vital role in your body—maintaining cellular balance and communicating oxidative stress levels. Here’s what you need to know: What They Are: Redox signaling molecules are like the traffic lights of your cells, ensuring everything flows smoothly and warning when something’s off. They help your body respond to stress and maintain balance at the cellular level. Impact: • Reactive Oxygen Species (ROS): Often misunderstood as purely damaging, ROS are actually crucial for cell signaling. They help your body defend against pathogens and are essential for cellular communication. However, when out of balance, they can contribute to oxidative stress and damage. • Nitric Oxide: This powerful signaling molecule plays multiple roles in your health. It helps regulate blood pressure by dilating blood vessels, supports your immune system, and even aids in neurotransmission. Nitric oxide is just one example of the multiple redox molecules that work together to keep your body functioning smoothly. Breaking Boundaries in Science: Today’s science has broken boundaries by stabilizing these redox-signaling molecules outside the human body, making it possible to replenish them daily. This breakthrough offers the ultimate global cellular biohack, allowing us to support and enhance our body’s natural signaling processes. Imagine boosting your body’s ability to communicate at the cellular level every day, promoting optimal health and wellness. Redox signaling is all about balance. When these molecules are functioning well, your cells thrive. But when there’s an imbalance, it can lead to issues like chronic inflammation, aging, and disease. By supporting your body’s natural redox processes through daily bioreplenishment, you can maintain that balance and harness the power of cutting-edge science for your health. #redoxsignalingmolecules #cellularhealth #carolynsconversations

From the desk of Dr. Carolyn Hoffman ………………. Understanding Redox Signaling Molecules: The Guardians of Cellular Balance ⚖️ Redox signaling molecules might sound complex, but they play a simple and vital role in your body—maintaining cellular balance and communicating oxidative stress levels. Here’s what you need to know: What They Are: Redox signaling molecules are like the traffic lights of your cells, ensuring everything flows smoothly and warning when something’s off. They help your body respond to stress and maintain balance at the cellular level. Impact: • Reactive Oxygen Species (ROS): Often misunderstood as purely damaging, ROS are actually crucial for cell signaling. They help your body defend against pathogens and are essential for cellular communication. However, when out of balance, they can contribute to oxidative stress and damage. • Nitric Oxide: This powerful signaling molecule plays multiple roles in your health. It helps regulate blood pressure by dilating blood vessels, supports your immune system, and even aids in neurotransmission. Nitric oxide is just one example of the multiple redox molecules that work together to keep your body functioning smoothly. Breaking Boundaries in Science: Today’s science has broken boundaries by stabilizing these redox-signaling molecules outside the human body, making it possible to replenish them daily. This breakthrough offers the ultimate global cellular biohack, allowing us to support and enhance our body’s natural signaling processes. Imagine boosting your body’s ability to communicate at the cellular level every day, promoting optimal health and wellness. Redox signaling is all about balance. When these molecules are functioning well, your cells thrive. But when there’s an imbalance, it can lead to issues like chronic inflammation, aging, and disease. By supporting your body’s natural redox processes through daily bioreplenishment, you can maintain that balance and harness the power of cutting-edge science for your health. #redoxsignalingmolecules #cellularhealth

🌟 Exciting News! 🌟 I am thrilled to share that my latest research on arterial stiffness has been published! This study delves into the intricacies of the active and passive components of the aortic tree, examining how these differ across various regions and how they change with aging. This work represents a step forward in understanding cardiovascular health and the mechanisms underlying regional arterial stiffness. For those interested in cardiovascular research and the regulatory dynamics of arterial stiffness, I invite you to read the full publication: https://lnkd.in/eznYJ_jd #Research #ArterialStiffness #Aging #Health #CardiovascularResearch #Publication

Unveiling the Hidden Maestro: How Our Body Orchestrates Its Defense Symphony 🎼🛡️ The image is suggestive of a graphic showing of a network of glowing nodes with lines connecting them, possibly with one node highlighted to represent the brain, orchestrating the rest of the network. Have you ever wondered who conducts the symphony of our body's defenses when faced with an invasion? 🤔 Recent research published in Nature has uncovered a remarkable conductor within us, a body-brain circuit that fine-tunes our immune responses like a maestro leading an orchestra. This groundbreaking study reveals how our bodies communicate imminent threats to the brain, which in turn, orchestrates a precise inflammatory response. Why is this important? Well, imagine a world where inflammation, often the root of many chronic diseases, could be controlled with the precision of a dimmer switch rather than a simple on/off toggle. This research addresses the long-standing problem of unregulated inflammation that can lead to conditions like arthritis, heart disease, and more. The study shows that specific neurons act as messengers, carrying signals of distress to the brain. The brain then adjusts the immune response, preventing it from spiraling out of control. It's a game-changer in our understanding of the immune system and opens doors to novel treatments that could one day fine-tune our body's response to disease. What more can be done? The potential is vast. Imagine therapies that could dial down inflammation in autoimmune diseases or boost it to fight infections more effectively. The possibilities for improving human health are as exciting as they are endless. #HealthInnovation #ImmuneSystem #InflammationControl #ChronicDiseasePrevention #MedicalResearch #ScienceForAll #BodyBrainConnection #NatureJournal

How Can Facial Temperature Transform Early Metabolic Disease Detection? Dr. Jing-Jong Han, Peking University, China, will join Skin Ageing & Challenges 2024 this November to discuss her latest findings on the innovative thermal imaging techniques for detecting aging disorders with a focus on the “ThermaFace Method”! A recent study led by her and colleagues at Peking University reveals that temperature variations in different facial regions can indicate chronic illnesses such as high blood pressure and diabetes. Using AI-derived thermal imaging, the researchers discovered significant patterns related to age and health status. Key Findings: 1️⃣ Nose temperature decreases with age, while eye area temperatures increase. 2️⃣ Elevated cheek temperatures correlate with higher blood pressure. Higher eye temperatures are found in individuals with metabolic disorders like diabetes and fatty liver disease. 3️⃣ Increased cellular activities related to inflammation, DNA repair, and infection response contribute to higher temperatures in specific facial regions. 4️⃣ A two-week regimen of jumping rope reduced participants' thermal age by five years, demonstrating the potential for lifestyle interventions. 🔗 Read more: https://lnkd.in/d5QVcxws. 📅 Join Us in November to stay updated on the latest innovations in health diagnostics! #SkinAgeingandChallenges #SkinAgeing2024 #health #innovation #AI #thermalimaging #bloodpressure #diabetes #inflammation #research

Professor @Paul Robbins from the University of Minnesota sheds light on cellular senescence and its impact on aging. His team is pioneering the development of senotherapeutics to mitigate the harmful effects of senescent cells. Discover how compounds like Fisetin and natural products like Fewcoiden are showing promise in reducing chronic inflammation and promoting healthy aging. Watch the video snippet to learn more about these groundbreaking discoveries! 🔬 Andrea B. Maier NUS Yong Loo Lin School of Medicine Centre for Healthy Longevity NUS Academy for Healthy Longevity #UHL24 #CellularSenescence #HealthyAging #Senotherapeutics #HeathyLongevity #Healthy #Longevity

Aging is not a disease. When we are young children, we age to become healthy adults. To declare aging as a disease essentially declares life itself as a disease. But later in life, for reasons that we still don’t fully understand, our bodies deteriorate, decline, and as time passes, this decline worsens. I was ready to invent new terminology for this stage when I remembered that we already have a scientific word to describe it, and that word is 'senescence,' introduced in 1891 by Charles Sedgwick Minot at the Physiological Laboratory of Harvard Medical School in a paper titled 'Senescence and Rejuvenation.' But there is a paradox here. Senescence also plays a crucial role in wound healing and other beneficial processes. When cells become senescent in response to damage or stress, they often aid in tissue repair and wound healing. So, an organism might have cells undergoing senescence for beneficial reasons, like wound healing, while still being generally healthy and not in a state of overall deterioration. Without a nuanced understanding, treatments aimed at combating senescence could inadvertently impair beneficial processes. Over the last century, senescence has become more associated with cells rather than whole organisms. This perspective shift has left a void in the effort to understand senescence at the level of the organism. Under what conditions would one declare a person to be senescent? The differentiation between aging, beneficial senescence, and detrimental senescence is a longstanding problem in longevity. Our mission is to recognize and distinguish these different motifs using biomarker information. #longevity #senescence #aging