Dartmouth Hitchcock Medical Center and Clinics’ Post

Why is mitochondrion so important for you? Over half of your body is mitochondria cells. You can not lift your arm without them. Mitochondria are extremely important for human health and function. Each cell can contain thousands of mitochondria, and the organs that require the most energy like the heart, brain, and muscles have the highest concentrations of mitochondria. Mitochondrial dysfunction is associated with aging, cancer, diabetes, cardiovascular disease, and neurodegenerative diseases. Maintaining healthy, well-functioning mitochondria is crucial for overall health and energy levels. Stay tuned for more... #cellsignaling #HumanBody #wellness #redoxmolecules

It was a pleasure to co-author a review with Michael Heneka on the inflammatory aspects of Alzheimer’s disease, published in Acta Neuropathologica. 📄 ▶ https://rdcu.be/dSjfz #Neuroinflammation #Neurodegeneration #Innateimmunity #AlzheimerDisease

Ten years ago, the sky-blue wavelengths of light were recognized as the most powerful circadian disruptors at night. Then we introduced Blue-Rich LED lights, and awarded the inventors a Nobel Prize. Why is it any surprise that obesity, diabetes, heart disease, and breast cancer rates are climbing rapidly? Sky-blue 480 nm light is almost 25 times more powerful at resetting circadian clocks than full-spectrum white light. In other words, you need approximately 1/25 of the watts of energy (see chart) to get the same circadian clock shift. That is why we need to avoid using conventional blue-rich white LED lights in the evenings and at night. Instead, use zero blue light in the evenings, or use eyewear that blocks 440-495nm blue light. For further details see THE LIGHT DOCTOR https://a.co/d/9epx7wt

This is one of many reasons people are tired, unmotivated, low dopamine... and eventually sick ...... our light health is affecting our circadian rhythms, and those out-of-synch body "clocks" are affecting EVERYthing else in our body. Heard the phrase "timing is everything"? Our cells run on internal clocks based on light/dark patterns, and their timing is our health; it's everything. Those internal clocks need both sunlight in the day and darkness at night, so that also includes screen time, because screens are light. Please read Dr. Moore-Ede's book on light. If you own a business or lead a team or have a family, I encourage you to learn how to increase wellbeing with healthier lighting and screen choices. Efficiency of bulbs (removing red) does NOT increase wellbeing of people. The over-emphasis on "efficiency" is a 1900s industrialist machinist term, and people are not machines. It's time to un-learn some of the things we learned in the 1900s. People > Efficiency

Reimagine Your Journey: Taking Control of Neurodegenerative Diseases with Personalized Digital Therapeutics For individuals facing a neurodegenerative disease, the prospect of managing a chronic condition can feel daunting. However, a promising revolution is unfolding, offering a glimmer of hope and empowerment: personalized digital therapeutics (PDT). This innovative approach is transforming the way we manage neurodegenerative diseases, shifting the focus from passive acceptance to active participation in your own brain health journey. Learn more at https://lnkd.in/eu5QDJS6 #neurodegenerative #dementiacare 

Cancer free Normal appearance visualized basal brain. There is no longer any tracer accumulation or asymmetry at base of tongue. The region was previously FDG avid has SUV max 3.1, prior 15.9. Contralateral base of tongue SUV max 3.1 and background blood pool SUV max 2.0. There is no longer focal FDG accumulation of right lower neck or bilateral level 2 neck nodes. Attenuation correction CT without contrast shows reduced size of nodes. These are better defined by contrast CT that was performed same day and will be reported separately. The metabolic appearance suggests complete resolution of nodal disease.

IntelGenx Corp. is repurposing Montelukast, originally FDA-approved for treating chronic asthma, to address mild to moderate Alzheimer’s disease. Montelukast works by blocking leukotriene receptors, reducing inflammation, and increasing the production of nerve cell progenitors, which can differentiate into neurons. With these therapeutic benefits, Montelukast shows promising potential in treating Alzheimer's, a disease characterized by inflammation and death of brain cells. Preliminary data is already showing encouraging results. Learn more: (https://lnkd.in/gcr65S6s). #DementiaTreatment #BrainHealth #ClinicalTrials #EndAlz

The Endotoxin Hypothesis of Alzheimer's Disease Lipopolysaccharides (LPS) are lipids that cause a strong inflammatory response in patients. The blood LPS levels in Alzheimer's disease patients are several-fold higher compared to age-matched controls. Guy C. Brown and Michael Heneka propose the following hypothesis: Elevated LPS levels contribute to the pathogenesis of Alzheimer's disease. How exactly LPS is contributing in detail is yet unknown, but the hypothesis provides many new possible routes of access into the treatment of neurodegenerative diseases. https://lnkd.in/e8icKXmR

  Brain tumors are a major global health concern that affect people of all ages. It can pose a greater risk to health. Understanding initial signs & symptoms is very important for prevention, diagnosis & treatment. There is a strong genetic reasoning to the risk of brain tumor development as well. People who have a family history of brain tumors or genetic abnormalities such as Turcot syndrome, Li-Fraumeni syndrome, neurofibromatosis, are more susceptible for causing the brain tumors. Therefore, do not ignore early signs and consult your doctor for further recommendations. Oncquest Laboratories limited offers comprehensive panels for diagnosis. To book your test now https://lnkd.in/dYBhupDz   #WorldBraintumorday #OncquestLabs #Diagnosis #CancerAwareness #HealthForAll #HealthRisk 

Did you know that Brain Tumours are among the 5 most common childhood cancers in South Africa? Brain tumour symptoms include: • Headaches • Dizziness and balance problems • Vision, hearing, or speech problems • Frequent vomiting Understanding brain tumour symptoms is important for early diagnosis and treatment/intervention, which can positively and significantly impact a child’s prognosis and quality of life. #ChildhoodCancerAwarenessMonth