Beckman Coulter Dx Eastern Europe’s Post

Between 2025 and 2050, antimicrobial resistance is projected to directly cause over 39 million deaths and be linked to a staggering 169 million deaths worldwide. One of the biggest challenges in combating AMR is navigating the complex pathway to prescriptions, which requires precise, timely, and actionable diagnostic insights. At Beckman Coulter Diagnostics, we provide advanced solutions to support healthcare providers in the fight against AMR: 🔬 Hematology: Reliable results to identify infections faster ➡️ https://lnkd.in/gUZcXG2 🧫 Microbiology: Enhanced detection and analysis of resistant pathogens ➡️ https://lnkd.in/ghQGbJ3Q 🚰 Urinalysis: Early and effective diagnostic pathways ➡️ https://lnkd.in/dnjRH7eZ Together, let’s combat AMR and build a healthier future for all. 🌟 #AMR #AntimicrobialResistance #SaveLives #AMRAwareness #Hematology #Microbiology #Urinalysis

Between 2025 and 2050, antimicrobial resistance is projected to directly cause over 39 million deaths and be linked to a staggering 169 million deaths worldwide. One of the biggest challenges in combating AMR is navigating the complex pathway to prescriptions, which requires precise, timely, and actionable diagnostic insights. At Beckman Coulter Diagnostics, we provide advanced solutions to support healthcare providers in the fight against AMR: 🔬 Hematology: Reliable results to identify infections faster ➡️ https://lnkd.in/gUZcXG2 🧫 Microbiology: Enhanced detection and analysis of resistant pathogens ➡️ https://lnkd.in/ghQGbJ3Q 🚰 Urinalysis: Early and effective diagnostic pathways ➡️ https://lnkd.in/dnjRH7eZ Together, let’s combat AMR and build a healthier future for all. 🌟 #AMR #AntimicrobialResistance #SaveLives #AMRAwareness #Hematology #Microbiology #Urinalysis

Between 2025 and 2050, antimicrobial resistance is projected to directly cause over 39 million deaths and be linked to a staggering 169 million deaths worldwide. One of the biggest challenges in combating AMR is navigating the complex pathway to prescriptions, which requires precise, timely, and actionable diagnostic insights. At Beckman Coulter Diagnostics, we provide advanced solutions to support healthcare providers in the fight against AMR: 🔬 Hematology: Reliable results to identify infections faster ➡️ https://lnkd.in/gUZcXG2 🧫 Microbiology: Enhanced detection and analysis of resistant pathogens ➡️ https://lnkd.in/ghQGbJ3Q 🚰 Urinalysis: Early and effective diagnostic pathways ➡️ https://lnkd.in/dnjRH7eZ Together, let’s combat AMR and build a healthier future for all. 🌟 #AMR #AntimicrobialResistance #SaveLives #AMRAwareness #Hematology #Microbiology #Urinalysis

Botulinum Neurotoxin characterization and testing Did you know that California has the highest rate of wound botulism in the United States? According to the California Department of Public Health https://lnkd.in/g_yi3tHN, this type of botulism is on the rise, posing serious health risks. Botulism is caused by Botulinum Neurotoxin, commonly known as botulinum toxin, a powerful substance derived from the bacterium Clostridium botulinum. In large doses, botulinum toxin can cause muscle paralysis and respiratory failure, which can be fatal if not treated promptly. Despite its potential dangers, botulinum toxin has a wide range of medical and cosmetic applications when used in controlled, small doses. In therapeutics, it is valued for its ability to temporarily paralyze muscles, allowing for the treatment of various conditions. This includes  ➡ Chronic migraines ➡ Muscle spasms such as those caused by dystonia and cervical dystonia  ➡ Spasticity in neurological disorders like multiple sclerosis and cerebral palsy ➡ Overactive bladder ➡ Hyperhidrosis (excessive sweating) When it comes to cosmetic applications, botulinum toxin is commonly known by brand names such as Botox®, used to temporarily reduce the appearance of wrinkles and fine lines. At BioTether Sciences, we have years long experience in developing and validating immunogenicity methods per GLP guidelines to assess anti-toxin antibodies in human serum, which is crucial for supporting clinical trials and drug development. "We have conducted in-depth studies on neurotoxins using cell-based assays and have characterized the associated proteins." says Erik Foehr, President and Leading Scientist at BioTether Sciences. Located in the North Bay, California, BioTether Sciences is a boutique Contract Research Organization (CRO) focusing on protein engineering, bioanalysis, genetics, cell based assays and medical device testing.  https://www.biotether.com/ We value our customers, and they value us for our affordable, tailored, and high-quality services. If you have a project in mind, we'd love to hear about it! Reach out to us anytime, and we'll be more than happy to discuss how we can best support you. #Botox #Botulinum Neurotoxin #Neurotoxin #Migrane #Cosmetics

How does the characterization of phage resistance in a cocktail targeting Pseudomonas aeruginosa contribute to our understanding of combating lung infections? Clara Leandro, scientific director at TechnoPhage, SA, will elaborate on this topic via a short oral talk at #TargetingPhageTherapy2024. The study characterizes the resistance profiles of Pseudomonas aeruginosa to a specific phage cocktail. It aids in optimizing phage cocktail formulations for better clinical outcomes in treating lung infections. Join us in Malta on June 20-21, 2024 to learn more! 🔗 Selected Short Orals: https://lnkd.in/gJwMuxGU 🌐 Conference Details: https://lnkd.in/egH62bTR #PhageTherapy2024 #bacteriophages #phagetherapy #antibiotics #antibioticresistance #infectiousdiseases #microbiology

sharing a new video addressing the ongoing blood culture bottle shortage. It covers: The origins of the shortage. Strategies for stewardship and resource management. Maintaining diagnostic accuracy and patient safety. Watch the video and share it to help spread the word on managing these challenges. #Healthcare #Microbiology #BloodCultureStewardship #PatientCare #LaboratoryMedicine #Diagnostics #ResourceManagement #ClinicalLaboratory

📃Scientific paper: Antimicrobial activity of D-amino acid in combination with photo-sonoactivated hypericin nanoparticles against Acinetobacter baumannii Abstract: Background The emergence of multidrug-resistant Acinetobacter baumannii strains is increasing worldwide. To overcome these life-threatening infections, the development of new treatment approaches is critical. For this purpose, this study was conducted to determine the antimicrobial photo-sonodynamic therapy (aPSDT) using hypericin nanoparticles (HypNP) in combination with D-Tryptophan (D-Trp) against A. baumannii . Materials and methods HypNP was synthesized and characterized, followed by the determination of the fractional inhibitory concentration (FIC) index of HypNP and D-Trp by checkerboard assay. Next, the antimicrobial and anti-biofilm potential of HypNP@D-Trp-mediated aPSDT against A. baumannii was evaluated. Finally, the anti-virulence activity of aPSDT using HypNP@D-Trp was accessed following the characterization of HypNP@D-Trp interaction with AbaI using in silico virtual screening and molecular docking. Results A synergistic activity in the combination of HypNP and D-Trp against A. baumannii was observed with a FIC index value of 0.5. There was a 5.10 log_10 CFU/mL reduction in the cell viability of A. baumannii when the bacterial cells were treated with 1/2 × MIC of HypNP@D-Trp and subsequently exposed to ultrasound waves and blue light ( P  < 0.05). Moreover, a significant biofilm degradation effect on biofilm-associated cells of A. baumannii was observed after treatment with aPSDT using 2 × MIC of HypNP@D-Trp in comparison with the control groups ( P  ... Continued on ES/IODE ➡️ https://etcse.fr/A34c ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you.

📃Scientific paper: Antimicrobial activity of D-amino acid in combination with photo-sonoactivated hypericin nanoparticles against Acinetobacter baumannii Abstract: Background The emergence of multidrug-resistant Acinetobacter baumannii strains is increasing worldwide. To overcome these life-threatening infections, the development of new treatment approaches is critical. For this purpose, this study was conducted to determine the antimicrobial photo-sonodynamic therapy (aPSDT) using hypericin nanoparticles (HypNP) in combination with D-Tryptophan (D-Trp) against A. baumannii . Materials and methods HypNP was synthesized and characterized, followed by the determination of the fractional inhibitory concentration (FIC) index of HypNP and D-Trp by checkerboard assay. Next, the antimicrobial and anti-biofilm potential of HypNP@D-Trp-mediated aPSDT against A. baumannii was evaluated. Finally, the anti-virulence activity of aPSDT using HypNP@D-Trp was accessed following the characterization of HypNP@D-Trp interaction with AbaI using in silico virtual screening and molecular docking. Results A synergistic activity in the combination of HypNP and D-Trp against A. baumannii was observed with a FIC index value of 0.5. There was a 5.10 log_10 CFU/mL reduction in the cell viability of A. baumannii when the bacterial cells were treated with 1/2 × MIC of HypNP@D-Trp and subsequently exposed to ultrasound waves and blue light ( P  < 0.05). Moreover, a significant biofilm degradation effect on biofilm-associated cells of A. baumannii was observed after treatment with aPSDT using 2 × MIC of HypNP@D-Trp in comparison with the control groups ( P  ... Continued on ES/IODE ➡️ https://etcse.fr/A34c ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you.

"A Place for Gentle Care, Laboratory" #srispectradiagosticsandclinic #laboratory #medicallaboratory #Laboratories #labtech #PatientCare #surgicalpathology #cytopathology #labdiscovery #medical #labtesting #tumourmarker #hormones #fertilitymarkers #drugassays #immunofluorescence #immunohistochemistry

A liposomal hydrogel for diagnostics in diabetic wounds? Does this work? Find out! 👇 Happy to announce a new project by Simon Matoori from Université de Montréal and Aristidis Veves from Beth Israel Deaconess Medical Center about the investigation of a hydrogen peroxide-sensing #liposomal #hydrogel for molecular #diagnostics in #diabetic wounds. How does it work? The overall goal of this research proposal is to develop fluorescent H2O2-sensing diagnostic wound dressing, and to test it in diabetic mouse wounds using a portable fluorometer. The dressing is composed of H2O2-sensing liposomal reaction compartments dispersed in an alginate hydrogel. After administration on the wound, H2O2-rich wound fluid diffuses into the hydrogel. H2O2 enters the liposomal lumen where it is used by horseradish peroxidase to oxidize the near-infrared fluorescent dye sulfo-cyanine 7, which results in an H2O2 concentration-dependent loss of fluorescence. The fluorescence decrease is detected by a portable fluorometer. 💡 More information on our webpage! #research #pharma #lipids #H2O2