Advion Interchim Scientific - Europe’s Post

Please join us on May 30th for an insightful webinar where we'll focus our discussion on the qualitative analysis of oligonucleotides using the HPLC-UV/MS method. Discover how this approach can offer you purity analysis, and molecular weight determination through charge deconvolution, etc., and gain access to valuable tricks and tips for optimizing oligonucleotide analysis. Additionally, learn how a streamlined method can provide both UV and MS analysis in a single run. Register now for this live webinar: https://lnkd.in/gSMcMxsW #LabManagement #AnalyticalChemistry #PrecisionResearch

Please join us on May 30th for an insightful webinar where we'll focus our discussion on the qualitative analysis of oligonucleotides using the HPLC-UV/MS method. Discover how this approach can offer you purity analysis, and molecular weight determination through charge deconvolution, etc., and gain access to valuable tricks and tips for optimizing oligonucleotide analysis. Additionally, learn how a streamlined method can provide both UV and MS analysis in a single run. Register now for this live webinar: https://lnkd.in/gSMcMxsW #LabManagement #AnalyticalChemistry #PrecisionResearch

Facing analytical challenges in bile acid analysis? We've got you covered! 👉 https://sciex.li/zdyuzp Learn about the intricate world of bile acids and the analytical challenges they present, from structural isomers to matrix effects Discover how advanced LC-MS/MS methods are paving the way for accurate detection and quantitation. #BileAcids #LCMSMS #MassSpectrometry #Metabolomics

Struggling to get reliable results in oligonucleotide analysis? Join us for an insightful webinar on May 30th at 9 AM EDT. Learn from Changtong Hao of Advion Interchim Scientific as he navigates the complex world of HPLC-UV/MS in qualitative oligonucleotide analysis. 🧪 Gain precision in your lab techniques, ensure accurate outcomes, and stay ahead in your research field. Don't miss out on this opportunity to enhance your lab's capabilities! 🌐 Register now to secure your spot: https://lnkd.in/g_nKJ_cH #HowItWorks #Oligonucleotides #PurityAnalysis #Webinar

In this latest article with Separation Science, Dr. Stephanie Marin discusses Sample Prep Workflows for Low-Level LC-MS/MS Analysis. Questions includes: 💡 A brief overview of liquid-liquid extraction (LLE), solid-liquid extraction (SLE), and solid-phase extraction (SPE) 💡 How LLE, SLE, and SPE compare in terms of efficiency, recovery, and reproducibility for endocrine testing 💡 The future of sample prep evolving, particularly for low-level endocrine testing Watch the full interview below: https://lnkd.in/g5U3k3yh #InTheNews

USA: TX: Differentiation of Δ9-THC and CBD Using Silver-Ligand Ion Complexation and Electrospray Ionization Tandem Mass Spectrometry (ESI-MS/MS)

Our Manuscript is accepted for publication in "Analytical Methods" "Exploring Glycated Sites in Human Serum Albumin: Impact of Sample Processing Techniques on Detection and Analysis"

Our next webinar from the API SCale-up Strategies is coming on July 16th! My colleagues Kuo-Chih Shih and Anne Virden will be talking about polymorphism and various ways of distinguishing between different drug substance forms and how to detect potential polymorphic impurities. Subscribe now and learn from our experts why understanding of polymorphic behavior of your API is so important.

🥳TGIF people! 🥳 It wouldn't be Friday without a new edition of "𝗧𝗵𝗲 𝗣𝗿𝗼𝘁𝗲𝗶𝗻 𝗣𝘂𝗿𝗶𝗳𝗶𝗲𝗿: 𝗘𝘅𝗽𝗲𝗿𝘁 𝗜𝗻𝘀𝗶𝗴𝗵𝘁𝘀, 𝗜𝗻𝗯𝗼𝘅 𝗗𝗲𝗹𝗶𝘃𝗲𝗿𝘆". Every Friday, we post a new technical article that you can read here on LinkedIn or have delivered directly to your inbox 📩 Our 8th article in this series is entitled "𝗢𝗽𝘁𝗶𝗺𝗶𝘇𝗶𝗻𝗴 𝘁𝗵𝗲 𝗯𝘂𝗳𝗳𝗲𝗿 𝗰𝗼𝗻𝗱𝗶𝘁𝗶𝗼𝗻𝘀 𝗳𝗼𝗿 𝗮 𝗴𝗹𝘆𝗰𝗼𝗽𝗲𝗽𝘁𝗶𝗱𝗲 𝗰𝗼𝗻𝗷𝘂𝗴𝗮𝘁𝗲 𝗔𝗣𝗜 𝗽𝘂𝗿𝗶𝗳𝗶𝗰𝗮𝘁𝗶𝗼𝗻". (What a title, right? This is some hardcore science. 😅) Here's a summary of what you'll learn after reading it: 🤹 Advantages of using IEX and RPC as orthogonal methods in peptide purifications 📃 A method for optimization of buffer conditions for IEX and RPC  🫸🫷 How high yield and high purity can achieved when using orthogonal methods https://lnkd.in/dJbk2tSz Use the above link ☝️ to get a copy delivered to your inbox, and follow us here🔔 to ensure that you don't miss any of the informative technical articles in this series.

In this paper, Szabolcs Fekete and Davy Guillarme explore the advantages of using ultra-short columns for analyzing large biomolecules. The review summarizes historical and recent works related to the use of short columns for therapeutic proteins, and outlines theoretical concepts, limitations and potential applications. The authors conclude that, considering all the benefits of ultra-short columns and their potential applications to other biomolecules and additional chromatographic modes, there is a great chance that ultra-short columns will be more widely considered in the future. https://bit.ly/3WlmUpm