Madrona

Imagine a future where healthcare isn’t just reactive but deeply personalized — where every patient gets the right treatment at the right time based on a precise understanding of their biology. This is the future Ovation is building, and on this week’s Founded & Funded, Madrona Partner Chris Picardo dives into it all with Ovation CEO Curt Medeiros. From transforming underutilized clinical data into rich multiomics datasets to forging industry-leading partnerships with companies like Illumina, Curt shares how Ovation is shaping the future of precision medicine. He also opens up about the challenges of building a scalable, privacy-first platform, the lessons he brought with him from leading large healthcare businesses, and why collaboration and diversity are key to solving complex problems in healthcare. This episode isn’t just a deep dive into Ovation’s journey — it’s a masterclass for founders building innovative companies. Listen or watch wherever you get your podcasts: YouTube: https://bit.ly/3BOk1Wl Spotify: https://spoti.fi/4fGVGiX Apple: https://apple.co/4fGVG2r Amazon: https://amzn.to/40iLPf1 Madrona (Full Transcript): https://bit.ly/4a0cqR4

Don't miss this great conversation with Chris Picardo & Curt Medeiros. The insights into building Ovation and tackling the challenges of scaling in precision medicine are invaluable. Excited to see what’s next for Ovation! YouTube: https://bit.ly/3BOk1Wl Spotify: https://spoti.fi/4fGVGiX Apple: https://apple.co/4fGVG2r Amazon: https://amzn.to/40iLPf1 Madrona (Full Transcript): https://bit.ly/4a0cqR4

Starting off the new year with a great podcast featuring Curt Medeiros from Ovation giving a masterclass in precision medicine. This is a perfect moment to share this discussion as data driven medicine moves into the spotlight, the broader field of Precision medicine is at a turning point, and Ovation is leading the way. In this week’s Founded & Funded, I had the pleasure of speaking with Curt Medeiros, CEO of Ovation, about how they are revolutionizing the field with diverse, multiomic data sets and cutting-edge partnerships. We discuss the challenges of scaling in healthcare, the importance of diversity in data, and why now is the moment for precision medicine beyond oncology. Madrona continues to be extremely excited about the future of AI and data driven medicine and Ovation is playing a crucial role in supporting the data side of this new paradigm. We've been investors since nearly day one - when Barry Wark and I first met in a long closed Seattle cafe - and have been lucky to support them on their entire journey! Whether you’re a founder looking to scale, an AI-enabled biotech or HealthTech enthusiast, or just curious about what the next decade of healthcare might look like, this episode is packed with insights you won’t want to miss. Tune in wherever you get your podcasts: YouTube: https://lnkd.in/gFGfzQ_C Madrona (Full Transcript): https://lnkd.in/gT3xNXzX

As we near the end of 2024, it’s always fun to reflect on the conversations and ideas that resonated with our audience the most. This year, Madrona’s top posts, podcasts, and videos showcased innovation and exploration across, of course, the AI agent landscape but also corporate travel transformation and go-to-market strategies. From blog posts that captured industry-shaping trends to podcasts that provided tactical advice for founders, here’s a roundup of Madrona’s most engaging content from the year (and some reflection on how it’s held up!) As we move into 2025, these stories and conversations remind us of how rapidly the world of technology, especially AI, is evolving. They also reflect the enduring importance of collaboration, innovation, and strategic thinking. You can take a deeper look back with us and explore the trends and ideas that will shape 2025 and beyond here: https://lnkd.in/gmK_w-Ty We’re excited to see what the next year holds and look forward to continuing to share insights that inspire and empower our community. Don't miss out — sign up for our newsletter here: https://lnkd.in/gZ3VSJ9K Steve Singh, Matt McIlwain, Jon Turow, S. Somasegar, Sabrina Wu, Vivek Ramaswami, Tim Porter

It is really no surprise that 2024 was another big year in AI. So what does AI in 2025 have in store? In a world where virtually every company claims to be “AI-powered,” it’s more difficult than ever to parse out what is “real” or not. Is that going to stop our Aspiring for Intelligence team from making predictions based on (some) data and (mostly) our intuitions? Absolutely not. Continuing their annual year-end tradition of making predictions in an inherently unpredictable market, Vivek Ramaswami and Sabrina Wu believe these five themes will have a major impact on AI in 2025. 1) Models shift from Pre-Training to Post-Training 2) Test-Time Compute Becomes the New Paradigm 3) Reasoning and Inference Chips Take Center Stage 4) Agents Are (Finally) Unleashed 5) Consolidation of GenAI Companies & New Business Models Emerge You can read the full post here: https://lnkd.in/gXm3cC9P What trends are you most excited about for 2025? Comment in the below!

You visited Madrona.com and LinkedIn to read these posts over and over again in 2024 — AI, Travel, Building with GenAI, and GTM. It's all here! Take a look back with us and explore the trends and ideas that will shape 2025 and beyond: https://lnkd.in/gmK_w-Ty Jon Turow Sabrina Wu Tim Porter Pradeep Rathinam May Habib Vivek Ramaswami Steve Singh Palak Goel Christal Bemont

We're excited to kick off the 2025 season of Founded & Funded with Ovation CEO Curt Medeiros on Jan. 2! Tune in wherever you get your podcasts to learn more about Curt's vision for Ovation and the unique journey that brought him to the company. Curt and Chris Picardo will dive into how Ovation is generating significant momentum with groundbreaking partnerships like this as well as exciting traction and a robust pipeline for 2025 and beyond. Curt also shares lessons he's learned along the way, tips for landing high-value customers, and his predictions for the future of data and precision medicine. Subscribe here to get the latest episodes when they drop: https://lnkd.in/gHpDBsDS

When was the last time you hired someone better than you at something? You’ve hired many amazing people. You’ve built teams. You know what “great talent” looks like... right? But here’s the twist: what works in one context doesn’t always work in a scrappy, chaotic startup environment. Even the most seasoned founders sometimes find themselves rethinking what “great” really means when hiring for their stage and challenges. This is the third installment of our Hooked on FRIQ'n Awesome series, where we tackle what it really means to know “What Great Looks Like” when hiring for your startup. We’re diving into: - Why “great is contextual.” - The signals and limiters. Thank you, Francois Ajenstat, for sharing your learnings about this very topic at Madrona's Builders Summit.

It's that time of the year again where Vivek Ramaswami and I make our annual AI predictions for 2025! From smarter, more efficient models to transformative business applications, 2025 will continue to push the boundaries of what’s possible in an “AI-powered” world. So, what key predictions will define 2025? 🤔 1️⃣ Models shift from Pre-Training to Post-Training 2️⃣ Test-Time Compute Becomes the New Paradigm 3️⃣ Reasoning and Inference Chips Take Center Stage 4️⃣ Agents Are (Finally) Unleashed 5️⃣ Consolidation of GenAI Companies & New Business Models Emerge You can read the full post below! What trends are you most excited for in 2025? Comment in the below!

To end the year we moved into our new, larger office in Palo Alto!! Thanks to the whole team who got involved to get everything moved in, hooked up, and running. And judging from the photo dump on this - Dasher (dog) was the star of the show. Hard to choose just one photo of him! Lots of great events planned for 2025 to show off this beautiful space! Karan Mehandru, Vivek Ramaswami, Anna Chen, Jeff Mills, Anna Baird, An Cayas, John Carpenter, Troy Cichos, Lena Klassen, Jennifer Chambers