Wishing you and your family a very happy, safe and prosperous Diwali !!! “May the lights of Diwali be an inspiration to overcome your hurdles and achieve your dreams.”
ChemScene
Chemical Manufacturing
Monmouth Junction, New Jersey 1,036 followers
Chemscene specializes in Buliding blocks, Bioactive small molecules, APIs and intermediate production, VD Series and CR
About us
About Us Headquartered in New Jersey, USA, ChemScence is a global leading manufacturer and supplier of building blocks and fine research chemicals. We now have branches in Sweden and India. Our mission is to pave the way for drug discovery by providing the most innovative chemicals with the highest levels of quality for a reasonable price. Our Team We have over 100 chemists and analysts, and half of the team hold Master's degree or higher. Our R&D team work closely with pharmaceutical and biotech companies, universities, and research institutions. With the effort of our highly experienced scientists, we now own over 4,000 ChemScene exclusive building blocks which are structurally novel. Our Facilities The R&D laboratory is more than 3,000 m² and is equipped with a range of facilities, allowing us to perform complex custom synthetic tasks on scales ranging from milligrams to hundreds of kilograms. The quality control management laboratory is equipped with high-performance liquid chromatograph, digital melting point apparatus, digital polarimeter, UV spectrophotometer, acidometer and other basic testing equipment. Quality Our strict quality control policy enables us to deliver quality chemicals into the marketplace. ChemScene provides you with relevant chemical testing data, such as HNMR, LC-MS and HPLC, as well as stability and activity information on all of our products. Our Catalog Products We deliver an extensive portfolio of products, including Building Blocks & Intermediates, Thin Layer Chromatography Plates, Bioactive Small Molecules, Natural Products, Peptides, Dyes and Bio-assay Reagents, Screening Libraries, etc. ChemScene now have over 45,000 Building Blocks & Intermediates in our catalog and more than 20,000 of them are in stock. In stock products will be shipped out on the same day upon receipt of customer’s purchase order. Products are offered at variable quantities and sizes to meet different customer needs.
- Website
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https://www.chemscene.com/
External link for ChemScene
- Industry
- Chemical Manufacturing
- Company size
- 501-1,000 employees
- Headquarters
- Monmouth Junction, New Jersey
- Type
- Partnership
Locations
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Primary
Get directions
1 Deer Park Dr, Suite Q
08852
Monmouth Junction, New Jersey 08852, US
Employees at ChemScene
Updates
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🎉 We’re Back from the Drug Discovery Strategic Summit (DDSS)! 🎉 We had a fantastic time at DDSS, connecting with industry innovators, exchanging insights, and learning about the latest trends in drug discovery. It was an excellent opportunity to showcase our solutions and engage with key players in the pharmaceutical and biotech sectors. We look forward to building on the connections made and continuing to support advancements in drug discovery. Thank you to everyone who stopped by! #DDSS2024 #DrugDiscovery #PharmaInnovation #GratefulForTheConnections #ChemScene
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Cyclic sulfones are important pharmacophores with a wide range of pharmacological activities owing to a range of mechanisms of action. Their ability to act as conformational constraint, H-acceptor and electron-withdrawing functionality has been used to improve affinity and potency by optimizing the interactions with the target proteins. The polarity associated with sulfones helps to reduce the overall lipophilicity, which in many cases translates into improvements in ADME (absorption, distribution, metabolism and excretion) and pharmaceutical properties. So far, Chemscene has developed many cyclic sulfone building blocks. For more information, please visit www.chemscene.com.
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Azaspirocycles, one of the representative spirocyclic compounds, are often seen in natural products and pharmaceuticals. Because of their three-dimensionality and rigidity, embedding an azaspirocycle into molecules is beneficial in medicinal chemistry. Azaspiro[2.5]octane features a spirocyclic structure where a piperidine ring is fused with a rigid cyclopropane ring. Recent research has shown that the incorporation of azaspiro[2.5]octane fragment into molecules can enhance their performance by improving biological activities and optimizing pharmacokinetics. So far, Chemscene has developed many Azaspiro[2.5]octane building blocks. For more information, please visit www.chemscene.com or contact us at sales@chemscene.com. #Azaspirocycles #MedicinalChemistry #Pharmaceuticals #DrugDiscovery #SpirocyclicCompounds #Chemscene #BuildingBlocks #ChemicalResearch #DrugDevelopment #OrganicChemistry
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Recently, Professor Eric N. Jacobsen's research group at Harvard University in the United States utilized a precisely designed chiral small molecule (646 Da) hydrogen bond donor (HBD) catalyst to accelerate the SN2 dealkylation step of the enantioselective Michaelis Arbuzov reaction by reproducing the geometric pre organization principle used by enzymes, thereby constructing a series of H-phosphonates with high enantioselectivity that can be derivatized in various ways. Mechanistic and computational studies have shown that although HBD reduces the reactivity of chloride nucleophiles, it can also reorganize phosphonium cations and chloride anions into a geometric structure that is prepared to enter the SN2 transition state, thereby accelerating the dealkylation step. The relevant results were published in Nature. For more information, please visit www.chemscene.com. #OrganicChemistry #Catalysis #Enantioselectivity #SN2Reaction #ChemScene
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